CDH17

(redirected from Liver-intestine cadherin)

CDH17

A gene on chromosome 8q22.1 that encodes cadherin 17, which is a component of the GI tract and pancreatic ducts, acting as an intestinal proton-dependent peptide transporter in the first step in oral absorption of medically important peptide-based drugs. Cadherin 17 may also play a role in the morphological organisation of the liver and intestine.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.
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References in periodicals archive ?
Cadherin 17 (CDH17), also called liver-intestine cadherin, is a cell-adhesion protein that is transcriptionally regulated by CDX2, and is involved in tumor invasion and metastasis.
Cadherin-17, also known as liver-intestine cadherin or human peptide transporter-1, is a structurally unique member of the cadherin superfamilies [6, 7].
Kreft et al., "Liver-intestine cadherin: molecular cloning and characterization of a novel Ca2+-dependent cell adhesion molecule expressed in liver and intestine," Journal of Cell Biology, vol.
Liver-intestine cadherin," Annals of the New York Academy of Sciences, vol.
CDH-17, also known as human peptide transporter-1 or liver-intestine cadherin, is regarded as a structurally unique member of the cadherin superfamily and regulates intercellular adhesion because it can retain its adhesive function without interacting with other cytoplasmic components (7,14).
[Expression of liver-intestine cadherin in gastric cancer and its relationship with progonsis].
Liver-intestine cadherin induction by epidermal growth factor receptor is associated with intestinal differentiation of gastric cancer.
Cadherin 17 (CDH17) is also known as liver-intestine cadherin because it was originally discovered as a novel calcium-dependent cell adhesion molecule expressed in the liver and intestine of rats.
Intestinal cell adhesion molecules: liver-intestine cadherin. Ann N YAcad Sci.
Involvement of liver-intestine cadherin in cancer progression.

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