Little disease

con·gen·i·tal spas·tic par·a·ple·gi·a

a type of cerebral palsy characterized by spastic paralysis of the lower extremities.
Farlex Partner Medical Dictionary © Farlex 2012

Little disease

[William John Little, Brit. physician, 1810–1894]
Congenital spastic paralysis usually on both sides (diplegia), although the disease may be paraplegic or hemiplegic in form. The affected child may be delayed in developing sphincter control but is usually normal mentally. Symptoms include stiff, awkward movements; legs crossed and pressed together; arm(s) adducted; forearm(s) flexed; hand(s) pronated; and scissors gait.
Medical Dictionary, © 2009 Farlex and Partners


William J., English surgeon, 1810-1894.
Little disease - a type of cerebral palsy in which there is bilateral spasticity, with the lower extremities more severely affected. Synonym(s): spastic diplegia
Medical Eponyms © Farlex 2012
References in classic literature ?
They told him of their little diseases, and, more important, the diseases of their tiny, sure-footed cattle; of trips as far as Kotgarh, where the strange missionaries live, and beyond even to marvellous Simla, where the streets are paved with silver, and anyone, look you, can get service with the Sahibs, who ride about in two-wheeled carts and spend money with a spade.
The very warm temperatures and dry weather may have played a part in the fact that Hatterman-Valenti reported seeing very little disease on the vines and not many insects.
With little disease to protect against, a vaccine trial is hard to conduct.
Keith, 66, added: "Some time ago I was diagnosed with a nasty little disease which affects one in three of us.
With information and conversation, maybe we can lure this hideous little disease out into the daylight so we can understand it better.
"There's a lot of HPV and very little disease" in women in their 20s, Castle added.
So it's officially infectious, and as Daily Mail puts it, " it's indeed a nasty little disease your marriage can catch from friends, relations and even work colleagues".
Infection is most common in ruminants and considered to cause little disease, but late abortions, metritis, mastitis and the birth of weak offspring with low vitality are seen.
He argues, in part, against use of the pandemic influenza A(H1N1) vaccine because he has seen little disease burden in his practice and throughout Maine.
"'We potentially excluded a large proportion of the treatment effect and biased our population toward those with more progressive disease," yet little disease progression was seen with combined therapy.
"Then when you pick patients whose joints are stable and have very little disease, you won't see significant changes on x-ray in two, short years.