(redirected from Lissencephaly syndrome type 1)


agyria. adj., adj lissencephal´ic.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.


Congenital lack or underdevelopment of the convolutional pattern of the cerebral cortex.
[G. a- priv. + gyros, circle]
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Neurology A brain malformation that is isolated or associated with other syndromes–eg, Miller-Dieker syndrome, Norman-Roberts syndrome, characterized by absence–agyria or incomplete development–pachygyria of cerebral gyri Clinical Microcephaly, seizures, profound mental retardation, feeding difficulties, growth retardation, impaired motor activity
McGraw-Hill Concise Dictionary of Modern Medicine. © 2002 by The McGraw-Hill Companies, Inc.


James Q., U.S. physician.
Miller-Dieker syndrome - arrested brain development. Synonym(s): lissencephaly; Norman-Roberts syndrome
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