lissencephaly

lissencephaly

 [lis″en-sef´ah-le]

agyria. adj., adj lissencephal´ic.

a·gy·ri·a

(ā-jī'rē-ă),

Congenital lack or underdevelopment of the convolutional pattern of the cerebral cortex.

Synonym(s): lissencephalia, lissencephaly

[G. a- priv. + gyros, circle]

lissencephaly

/lis·sen·ceph·a·ly/ (lis″en-sef´ah-le) agyria.lissencephal´ic

lissencephaly

See agyria.

lissencephaly

Neurology A brain malformation that is isolated or associated with other syndromes–eg, Miller-Dieker syndrome, Norman-Roberts syndrome, characterized by absence–agyria or incomplete development–pachygyria of cerebral gyri Clinical Microcephaly, seizures, profound mental retardation, feeding difficulties, growth retardation, impaired motor activity

Miller,

James Q., U.S. physician.

Miller-Dieker syndrome - arrested brain development. Synonym(s): lissencephaly; Norman-Roberts syndrome

lissencephaly

a malformation in which the gyri of the cerebral cortex are not normally developed. In dogs it has been associated with behavioral abnormalities, visual deficits, ataxia and seizures. Called also agyria.