lisofylline


Also found in: Wikipedia.

lisofylline

Infectious disease An investigational antibiotic for treating serious infections in CA Pts immunocompromised by therapy–eg, induction chemotherapy for AML, high-dose RT and/or chemotherapy followed by BMT
Mentioned in ?
References in periodicals archive ?
Bhat VB, Madyastha KM (2001) Antioxidant and radical scavenging properties of 8-oxo derivatives of xanthine drugs pentoxifylline and lisofylline.
Madyastha, "Antioxidant and radical scavenging properties of 8-oxo derivatives of xanthine drugs pentoxifylline and lisofylline," Biochemical and Biophysical Research Communications, vol.
The company stated that lisofylline and its analogues have been indicated to inhibit activation of pro-inflammatory immune signalling molecules IL-12 and STAT4, but clinical utility of these compounds has been limited by poor drug qualities.
Lisofylline (LSF), the first product in their pipeline, has been demonstrated in animal studies to reverse type 1 diabetes when used in combination with another agent.
Celebrate because type 1 diabetes may be reduced or prevented through the use of an anti-inflammatory drug, lisofylline, according to Dr.
The drag, lisofylline, slows the production of the immune-system proteins interferon-gamma and tumor necrosis factor-alpha.
Bhat VB and Madyastha KM (2001) Antioxidant and Radical Scavenging Properties of 8-Oxo Derivatives of Xanthine Drugs Pentoxifylline and Lisofylline.
For example, using a type of 13 000-oligonucleotide chips, a gene expression study on a murine model for type I diabetes has recently been performed to compare the effects of cytokine mediation and treatment with the antiinflammatory agent lisofylline (LSF) in autoimmune diabetes (10).