lipoxygenase

(redirected from Lipoxygenases)

lipoxygenase

 [lĭ-poks´ĭ-jĕ-nās]
an enzyme that catalyzes the oxidation of polyunsaturated fatty acids to form a peroxide of the acid.

lipooxygenase

, lipoxygenase (lip-ooks'ĭ-jen-ās, lip-oks'ĭ-jen-ās),
Any of a family of enzymes that convert unsaturated fatty acids to peroxides; important in the synthesis of leukotrienes from arachidonic acid.
[lipo- + oxygen + -ase]

lipoxygenase

/li·poxy·ge·nase/ (lĭ-pok´sĭ-jĕ-nās) an enzyme that catalyzes the oxidation of polyunsaturated fatty acids to form a peroxide of the acid.

li·pox·y·ge·nase

(li-poks'ē-jĕ-nās)
An enzyme that catalyzes the oxidation of unsaturated fatty acids with O2 to yield hydroperoxides of the fatty acids.
Synonym(s): lipoxidase.

lipoxygenase

An enzyme that catalyzes the production of leukotrienes from arachidonic acid.

lipoxygenase (lipˈ·äkˑ·s·j·nās),

n catalytic enzyme that facilitates the synthesis of leukotrienes by converting arachidonic acid to hydroxyeicosenoic acid via an oxidative process.
Enlarge picture
Lipoxygenase.

li·pox·y·ge·nase

(li-poks'ē-jĕ-nās)
An enzyme that catalyzes the oxidation of unsaturated fatty acids with O2 to yield hydroperoxides of the fatty acids.
Synonym(s): lipoxidase.

lipoxygenase

(lipok´səjənās´),
n an enzyme that catalyzes the oxidation of unsaturated fatty acids with O2 to form peroxides of the fatty acids.

lipoxygenase

an enzyme that catalyzes the oxidation of polyunsaturated fatty acids to form a peroxide of the acid.
References in periodicals archive ?
Drugs that target lipoxygenases and leukotrienes as emerging therapies for asthma and cancer.
The inhibition of various enzymes of the arachidonic acid cascade, among these the lipoxygenases and the cyclooxygenases, might be a possible target.
Through its recently established metabolic disease program, Galileo confirmed in preclinical models that inhibiting lipoxygenases, known mediators of inflammatory response, significantly lowers blood glucose levels in animal models of diabetes.
Lipoxygenases are dioxygenases found ubiquitously in higher plants and animals.
This laboratory is studying the expression of prostaglandin H synthases and lipoxygenases in the development of colon, breast, and other cancers.
GLA is further metabolized to dihomogamma linlenic acid (DGLA) which undergoes oxidative metabolism by cyclooxygenases and lipoxygenases to produce anti-inflammatory eicosanoids (prostaglandins of series 1 and leukotrienes of series 3).
lipoxygenases, cyclooxygenases, topoisomerases, human leucocyte elastase and I[kappa]B kinases are a matter of debate.
We have identified potent, selective modulators of therapeutically important target classes such as kinases, lipoxygenases and PPAR modulators, and our results to date indicate that our discovery platform will enable us to approach these important target classes.
2], inhibitors of COX, inhibitors of lipoxygenases, inhibitors of elastase and inhibitors of NO synthase.
We found it beneficial to examine the lipid peroxidation property of knipholone as polyphenols in general can influence the lipid peroxidation process by affecting the activity of enzymes such as lipoxygenases and cycloxygenases (Cao et al.
Lipoxygenase inhibitors attenuate growth of human pancreatic cancer xenografts and induce apoptosis through the mitochondrial pathway.
They constitute an array of compounds that have various combination effects of inhibiting both COX-2 and COX-1, in addition to the lipoxygenase (LOX) and phospholipase A2 enzymes.