Evidences also suggest that amyloidogenic amyloid precursor protein (APP) processing might preferentially occur in the cholesterol-rich regions of membranes known as lipid rafts
and that alterations in cholesterol levels could exert their effects by altering the distribution of APP-cleaving enzymes within the membrane.
The subject of the public contract will be used for the development of vaccines, Diagnostics and teranosities, Including on the basis of targeted nanoparticles, In the study of lipid membranes and lipid rafts
Macrophage ABCA1 reduces MyD88-dependent Toll-like receptor trafficking to lipid rafts
by reduction of lipid raft
C] is a highly conserved glycoprotein localized in membrane lipid rafts
and anchored to the cell surface by glycosylphpsphatidylinositol (GPI) (28, 29) Pr[P.
and raft- mediated supramolecular entities in the regulation of CD95 death receptor apoptotic signaling.
The mechanisms responsible for the targeting of CD1 molecules from the lysosome to the plasma membrane are not well understood, but it is known that localization of these molecules in lipid rafts
improves antigen presentation .
These cells--originally derived from a human-prostate cancer and containing prostasome membranes enriched in lipid rafts
of cholesterol and sphingomyelin (Llorente et al.
These lipid rafts
play a central role in the lifecycles of hepatitis viruses.
Mycobacterium tuberculosis lipoprotein-induced association of TLR2 with protein kinase C zeta in lipid rafts
contributes to reactive oxygen species-dependent inflammatory signalling in macrophages.
Isolation and biochemical characterisation of lipid rafts
from Atlantic cod (Gadus morhua) intestinal enterocytes.
Ceramides constitute an important part of cell membrane, being localized mainly in lipid rafts
Too much cholesterol increases the abundance of lipid rafts
, areas in the plasma membrane where surface receptors initiate signaling events leading to angiogenesis," Miller said.