lipid raft

(redirected from Lipid rafts)

lipid raft

(lip'id raft),
Detergent-insoluble raft microdomains that are enriched in sphingolipids and cholesterol, found in the plasma membrane, late secretory pathway, and endosomal compartments.

lipid raft

A tiny cholesterol-rich region on a cell membrane that helps selected molecules enter the cytoplasm.
Synonym: lipid domain
See also: raft
Mentioned in ?
References in periodicals archive ?
Evidences also suggest that amyloidogenic amyloid precursor protein (APP) processing might preferentially occur in the cholesterol-rich regions of membranes known as lipid rafts and that alterations in cholesterol levels could exert their effects by altering the distribution of APP-cleaving enzymes within the membrane.
The subject of the public contract will be used for the development of vaccines, Diagnostics and teranosities, Including on the basis of targeted nanoparticles, In the study of lipid membranes and lipid rafts.
Macrophage ABCA1 reduces MyD88-dependent Toll-like receptor trafficking to lipid rafts by reduction of lipid raft cholesterol.
C] is a highly conserved glycoprotein localized in membrane lipid rafts and anchored to the cell surface by glycosylphpsphatidylinositol (GPI) (28, 29) Pr[P.
Lipid rafts and raft- mediated supramolecular entities in the regulation of CD95 death receptor apoptotic signaling.
The mechanisms responsible for the targeting of CD1 molecules from the lysosome to the plasma membrane are not well understood, but it is known that localization of these molecules in lipid rafts improves antigen presentation [39].
These cells--originally derived from a human-prostate cancer and containing prostasome membranes enriched in lipid rafts of cholesterol and sphingomyelin (Llorente et al.
These lipid rafts play a central role in the lifecycles of hepatitis viruses.
Mycobacterium tuberculosis lipoprotein-induced association of TLR2 with protein kinase C zeta in lipid rafts contributes to reactive oxygen species-dependent inflammatory signalling in macrophages.
Ceramides constitute an important part of cell membrane, being localized mainly in lipid rafts [21].
Too much cholesterol increases the abundance of lipid rafts, areas in the plasma membrane where surface receptors initiate signaling events leading to angiogenesis," Miller said.