lipid raft


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Related to lipid raft: Caveolae

lipid raft

(lip'id raft),
Detergent-insoluble raft microdomains that are enriched in sphingolipids and cholesterol, found in the plasma membrane, late secretory pathway, and endosomal compartments.

lipid raft

A tiny cholesterol-rich region on a cell membrane that helps selected molecules enter the cytoplasm.
Synonym: lipid domain
See also: raft
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References in periodicals archive ?
Gould, "The vesicle- and target-SNARE proteins that mediate Glut4 vesicle fusion are localized in detergent-insoluble lipid rafts present on distinct intracellular membranes," The Journal of Biological Chemistry, vol.
Camerini et al., "Exogenous alpha-synuclein alters pre- and post-synaptic activity by fragmenting lipid rafts," EBioMedicine, vol.
In fact, the virus particles share the outer lipid coat with certain structures (i.e., lipid rafts, which will be discussed below) in the cell membrane surrounding the host hepatocytes (Chang et al.
I recorded whether these coordinates resulted in a "hit" on the opposing team's lipid rafts on blank grids on the overhead projector.
Early studies using differential centrifugation reported that mammalian T-tubule membranes have a high proportion of cholesterol and sphingolipids [9] which resemble the composition of cholesterol-enriched lipid rafts domains [11].
The membrane lipid rafts are cholesterol- and sphingomyelin-rich membrane microdomains and indicate an important feature that may contribute to signalings through the plasma membrane.
Accumulating evidence suggests that HDL or a specific apolipoprotein associated with HDL, such as apoA-I, is involved in the innate and adaptive immune responses primarily through the modulation of lipid raft components in monocytes/macrophages, dendritic cells, and T and B lymphocytes.
Tsokos, "Cholera toxin B accelerates disease progression in lupus-prone mice by promoting lipid raft aggregation," Journal of Immunology, vol.
Because of its unique fatty acid composition, PtdGlc has physical properties similar to those of GlcCer, which in turn can lead to the formation of lipid microdomains or lipid rafts. The biological functions of this new glycolipid are also discussed in this review.
Lipid raft isolation using sucrose density gradient method enabled us to study the signaling proteins involved in this process.
Mouradian et al., "Docosahexaenoic acid alters epidermal growth factor receptor-related signaling by disrupting its lipid raft association," Carcinogenesis, vol.