Lineweaver-Burk equation

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Line·weav·er-Burk e·qua·tion

(līn'wē-vĕr bŭrk),
a rearrangement of the Michaelis-Menten equation, 1/v = 1/Vmax + (Km/Vmax)(1/[S]), where v is the velocity of the reaction, Vmax is the maximum velocity, Km is the Michaelis constant; and [S] is the substrate concentration. Compare: double-reciprocal plot.
[Hans Lineweaver, Dean Burk]
Farlex Partner Medical Dictionary © Farlex 2012


Dean, U.S. scientist, 1904–.
Lineweaver-Burk equation - see under Lineweaver
Lineweaver-Burk plot - see under Lineweaver


Hans, U.S. physical chemist, 1907–.
Lineweaver-Burk equation - rearrangement of the Michaelis-Menten equation.
Lineweaver-Burk plot - graphical representation of enzyme kinetic data. Synonym(s): double-reciprocal plot; Woolf-Lineweaver-Burk plot
Medical Eponyms © Farlex 2012
References in periodicals archive ?
The Lineweaver-Burk equation, shown below, was used to evaluate the [K.sub.m] of trypsin:
The value of 1/[S] was plotted versus 1/V according to the Lineweaver-Burk equation.
The static quenching constant [K.sub.LB] (Table 2) was developed by the Lineweaver-Burk equation
The kinetics of free and immobilized enzymes, which were determined in the absence and presence of Cu, obeyed the Lineweaver-Burk equation [24].