Pregnancy Category: UK
ClassificationTherapeutic: nonopioid analgesics
Dietary management of osteoarthritis; considered to be a medical food product.
Anti-inflammatory and analgesic properties related to inhibition of prostaglandin synthesis by inhibiting cyclo-oxygenase (not COX-2 selective) and other mediators of inflammation.
Decreased pain/inflammation associated with osteoarthritis, with improved mobility.
Absorption: Some intestinal conversion prior to absorption, remainder unknown.
Metabolism and Excretion: Mostly metabolized by the liver.
Time/action profile (analgesic effect)
|PO||within 1–2 hr||unknown||12 hr|
Contraindicated in: Hypersensitivity; Obstetric / Lactation / Pediatric: Not recommended.
Use Cautiously in: History of GI bleeding.
Adverse Reactions/Side Effects
- ↑ BP
- ↑ in varicose veins
- GI upset
Drug-Drug interactionNone noted.
Oral (Adults) 250 mg every 12 hr (up to 250 mg three times daily has been used).
Capsules: 250 mg
- Assess pain (note type, location, and intensity), range of motion, degree of swelling, and stiffness in affected joints before and periodically during therapy.
Potential Nursing DiagnosesChronic pain (Indications)
- Oral: Administer flavocoxid twice daily.
- Instruct patient to take flavocoxid as directed. Do not increase does without consulting health care professional.
- Decrease in pain and stiffness, and improved mobility in patients with osteoarthritis.