paraneoplastic limbic encephalitis

(redirected from Limbic encephalitis)
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paraneoplastic limbic encephalitis

Abbreviation: PNLE
A brain disorder occurring in some patients with cancer, characterized by the rapid onset of memory loss, often with temporal lobe disease, seizures, delirium, or disturbances of mood. Patients with PNLE often have antibodies against tumor antigens that also react with nerve cell antigens. In some patients the neurological disorder improves after treatment of the responsible tumor.
See also: encephalitis
References in periodicals archive ?
Antibodies to Kv1 potassium channel-complex proteins leucinerich, glioma inactivated 1 protein and contactin-associated protein-2 in limbic encephalitis, Morvan's syndrome and acquired neuromyotonia.
The current neurological presentation is due to paraneoplastic limbic encephalitis.
The patient was treated with salvage chemotherapy and, on follow-up imaging, the nodal masses were noted to be much smaller, the hepatic metastases had cleared completely, the limbic encephalitis changes had resolved, and there was normalisationvw of tumour markers.
Location of paraneoplastic neurological syndrome and subtypes described Brain Limbic encephalitis Brainstem encephalitis Cerebellar degeneration Opsoclonus-myoclonus Visual syndromes--cancer-associated retinopathy, optic neuritis Extrapyramidal syndromes--chorea, parkinsonism Spinal cord Necrotising myelopathy Inflammatory myelitis Motor neuron dise ase Stiff person syndrome Subacute motor neuropathy Dorsal root Sensory neuropathy ganglion Peripheral Autonomic neuropathy nerve Acute sensorimotor neuropathy, e.
SAN FRANCISCO -- Limbic encephalitis, which is usually blamed on an immune response to a tumor, also occurs in patients with no evidence of a tumor, Dr.
She described 11 patients with limbic encephalitis and no evidence of a tumor.
Human herpesvirus 6 limbic encephalitis after stem cell transplantation.