ionotropic

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ionotropic

(ī″ŏn-ŏ-trō′pĭk) [″ + ″]
Having an influence on glutamate-gated cell surface receptors, i.e., on cell membrane channels that open or close in the presence of ions.
References in periodicals archive ?
Receptors can be sorted into 4 broad categories: ligand-gated ion channels, G-protein-coupled receptors, kinase-linked receptors, and nuclear receptors.
2] Nonstandard abbreviations: WAT, white adipose tissue; UCP1, uncoupling protein 1; ASC-1, neutral amino acid transporter, y+ system, also called solute carrier family 7 member 10, slc7a10; PET/CT, positron emission tomography-computed tomography; PAT-2, proton/amino acid symporter member 2, also called solute carrier family 36 member 2, slc36a2; P2RX5, purinergic receptor P2X, ligand-gated ion channel 5.
They noted a protein sequence on the bacteria that is remarkably similar to the sequence of a group of ligand-gated ion channels in the human brain.
Functional architecture of the nicotinic acetylcholine receptor: a prototype of ligand-gated ion channels.
Over the last two decades, numerous studies have shown that alcohol affects many different types of ion channels, including ligand-gated ion channel receptors (Narahashi et al.
The nAChRs belong to the cys-loop superfamily of ligand-gated ion channels, which also includes [lambda]-aminobutyric acid (GABA)-gated Cl- channels, glycine receptors, glutamate-gated Cl- channels, and 5-hy droxytryptamine type 3 (5-HT3) receptors (Lester et al.
Evolutionary relationship of the ligand-gated ion channels and the avermectin-sensitive, glutamate- gated chloride channels, J.
The cys-loop family of ligand-gated ion channels (LGICs) consists of the nicotinic acetylcholine, serotonin type-3 (5-HT3), glycine, and GAB[A.
They explained, "Brain nicotinic acetylcholine receptors are a family of ligand-gated ion channels, and high-affinity nicotine binding is associated with receptors composed of [[alpha].
ATP has a dual role as both an energy source for enzymatic reactions and as a first messenger for several classes of G protein-coupled receptors and ligand-gated ion channels.
CLEVELAND -- Beginning next month, ChanTest Corporation will offer the highest throughput electrophysiology platform on the market validated for both voltage-gated (VGIC) and rapidly desensitizing ligand-gated ion channels (LGICs).
Neuronal nicotinic receptors (NNRs) belong to the Cys-loop family of ligand-gated ion channels, are formed from five subunits either as homologous or heterologous, oligomeric receptors, and are of interest as targets for treatment of a variety of central and peripheral nervous system disorders.