Leydig cells


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Related to Leydig cells: FSH, corpus luteum, androgen, Leydig cell tumor

in·ter·sti·tial cells

1. cells between the seminiferous tubules of the testis that secrete testosterone; Synonym(s): Leydig cells
2. cells derived from the theca interna of atretic follicles of the ovary; they resemble luteal cells and are an important source of estrogens;
3. pineal cells similar to glial cells with long processes.

in·ter·sti·tial cells

(in'tĕr-stish'ăl selz)
1. Cells between the seminiferous tubules of the testis that secrete testosterone.
Synonym(s): Leydig cells.
2. Cells derived from the theca interna of atretic follicles of the ovary; they resemble luteal cells and are an important source of estrogens.
3. Pineal cells similar to glial cells with long processes.

Leydig cells

Cells lying between the seminiferous tubules in the testis that secrete testosterone. (Franz Leydig, 1821–1908, German zoologist).

Leydig cells

or

interstitial cells

the cells of the testes that secrete TESTOSTERONE when stimulated by LUTEINIZING HORMONE.

Leydig cells

Cells that make up the endocrine tissue of the testis and produce testosterone. They are named for Franz von Leydig (1821–1908), the German professor of anatomy who first identified them.
Mentioned in: Klinefelter Syndrome

Leydig,

Franz von, German anatomist, 1821-1908.
Leydig cell adenoma - small benign tumors of the testis that often produce testosterone, causing endocrine symptoms. Synonym(s): interstitial cell tumor of testis
Leydig cells - cells between the seminiferous tubules of the testis that secrete testosterone. Synonym(s): interstitial cells
Leydig drain
Leydig duct - embryonic duct which becomes ductus deferens in males.
References in periodicals archive ?
A new variant in signal peptide of the human luteinizing hormone receptor (LHCGR) affects receptor biogenesis causing leydig cell hypoplasia.
* The administration of BD in mice improved male reproductive parameters such as increasing sex hormone levels (FSH, LH, and testosterone), sperm quality, and Leydig cell number with no effect on the level of androgen receptor gene expression.
The interstitium is composed of vascular loose fibrous connective tissue and Leydig cells.
Treating the cells with L-NAME, a NOS inhibitor, revealed that basal NO, at least in Leydig cells, was not enough to significantly modify the amplitude of the ATP-induced currents.
Positive immuno-staining of CYP17 was exclusively localized in the Leydig cells. Bars = 10 [micro]m and bars in inserts = 5 [micro]m.
Chemerin, CMKLR1, and GPR1 are localized specifically on Leydig cells and poorly on germ cells [16].
In adult rat Leydig cell cultures, both retinol and retinoic acid-enriched media showed a direct stimulatory effect on testosterone biosynthesis via 3[beta]-HSD compared to control media, as measured by radioimmunoassay.
Theophylline, a caffeine metabolite and pharmaceutical used in the treatment of asthma had previously been shown to impair Leydig cell development in the rat (Pollard et al.
They screened 11 transcription factors that could affect the ability of Leydig cells to produce testosterone.
As the primary source of synthesizing and secreting testosterone in mammalian testes, adult Leydig cells (ALCs) play essential roles in maintaining vital movement [3].
The seminiferous tubules and Leydig cells were quantified by a stereological method [12-14].
Many studies have demonstrated that LOH is closely linked to a deficiency in serum testosterone levels [1-3] because the total number of Leydig cells, which are the main source of testosterone in middle-aged men, decreases to about a half of that seen in young men [4, 5].