Benign lesions that were histopathologically diagnosed included mature teratoma, adenomatoid tumour, granulomatous orchitis, chronic orchitis, epididim-orchitis, epididymal cyst, Leydig cell tumour
, Sertoli cell tumour, fibrous pseudotumour, tunica albugenia cyst, epidermal cyst, leiomyoma, fibroma, juvenile granulosa cell tumour, granulomatous epididymitis, and microlithiasis with epididymal abscess.
Hemorrhagic shock caused by rupture of an intra-abdominal leydig cell tumour
: Case Report.
The post-operative period was uneventful .The histopathology report came out to be well differentiated Sertoli leydig cell tumour. The other structures showed no metastatic deposits and it was considered stage 1tumour .Oncologist opinion was obtained and he suggested regular follow up.
DISCUSSION: Our case is a low grade Sertoli leydig cell tumour (SLCT) presenting in a young female.
A differential diagnosis of this tumour includes a steroid cell tumour (stromal luteoma, Leydig cell tumour
, steroid cell tumour, not otherwise specified, dysgerminoma, and a clear cell variant of struma ovarii.[sup.12,13]
Aigner et al., "Increased incidence of Leydig cell tumours
of the testis in the era of improved imaging techniques," BJU International, vol.
Of these 36( 76 %)were granulosa cell tumours (adult 33, juvenile 3), 7 were labeled as sertoli leydig cell tumours
(15%), 3 as thecoma/ fibroma group (7%) and only one case was labeled as microcystic stromal tumour of the ovary (2%).
Cecchetto et al., "Ovarian Sertoli Leydig cell tumours
in children and adolescents: an analysis of the European Cooperative Study Group on pediatric rare tumors (EXPeRT)," European Journal of Cancer, vol.
Mandard, "Luteinizing hormone regulation by sex steroids in men with germinal and Leydig cell tumours
," Clinical Endocrinology, vol.
Neuroendocrine characteristics of human Leydig cell tumours
Adenomatous hyperplasia with increased ACTH production can occur independently or in association with similar changes in the native adrenals.[sup.1] The development of a neoplasm in an ectopic adrenal deposit is uncommon, yet phaeochromocytoma and Leydig cell tumours
have been reported.[sup.10] Primary neoplastic tissue in the spermatic cord is also rare, but paragangliomas have been described.[sup.11]
Osseous metaplasia has been documented in well differentiated Sertoli, Leydig cell tumours
, mucinous cystadenoma, fibromas and serous papillary cystadenocarcinoma [8,9].