Leydig cell tumor


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Related to Leydig cell tumor: Leydig cells, interstitial cell tumor

Ley·dig cell tumor

(lī'dig),
a testicular and, less commonly, ovarian neoplasm composed of Leydig cells, usually benign but may be malignant; may secrete androgens or estrogens.
Synonym(s): interstitial cell tumor of testis

Ley·dig cell tu·mor

(lī'dig sel tū'mŏr)
A testicular and, less commonly, ovarian neoplasm composed of Leydig cells, usually benign but may be malignant; may secrete androgens or estrogens. Causes gynecomastia in adults and precocious sexual development in prepubescents.
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References in periodicals archive ?
Primary tumors of the testes, such as Leydig cell tumors, can also serve as uncommon reason for gynecomastia.
Two Years of Gynecomastia Caused by Leydig Cell Tumor
The expression of EG-VEGF, both at mRNA and protein level, was restricted to the Leydig cell tumors [80].
Endocrine Gland-Derived Vascular Endothelial Growth Factor/Prokineticin-1 in Cancer Development and Tumor Angiogenesis
The rare diagnosis of a synchronous Leydig cell tumor and seminoma can be made but it is important to distinguish these tumors from one another and from other malignancies due to different treatment strategies, especially in the event of recurrence.
Synchronous Leydig Cell Tumor and Seminoma in the Ipsilateral Testis
(5,8) Granulosa cell tumor was the most common tumor (75%) observed in this group with one case of sertoli leydig cell tumor.
Pattern of ovarian neoplasm in rural population: a five year study from tertiary care hospital
* Leydig cell tumors, not otherwise specified steroid cell tumors, not otherwise specified (NOS)
Masculinising ovarian steroid cell tumor in a 51 year old Indian female: a case report
Virilizing stromal Leydig cell tumor of the ovary in pregnancy-A Case Report.
Ovarian Sertoli-Leydig cell tumor: a rare tumor with atypical presentation
(b) SF-1 is a good marker for steroidogenic tumors, including Leydig cell tumors and Sertoli cell tumors, and it shows negativity in all GCTs; however, there is no published data on its expression in the other SCSTs.
The Application of Immunohistochemical Biomarkers in Urologie Surgical Pathology
Leydig cell tumor differs from Leydig cell hyperplasia by being solitary, whereas nodular Leydig cell hyperplasia is characteristically multifocal.
An in-depth look at Leydig cell tumor of the testis
Leydig cell tumor of the testis associated with Klinefelter's syndrome and Osgood-Schlatter disease.
Postmortem diagnosis of "occult" Klinefelter syndrome in a patient with chronic renal disease and liver cirrhosis. (Case Reports)
This report shows the presence of epigenetic control of NIS expression in Leydig cell tumors (14).
Sodium Iodide Symporter Protein Expression and Clinicopathological Variables in Pure Testicular Seminomas
Sertoli-stromal tumors, also known as Leydig cell tumors, are rare, androgen-secreting, virilizing tumors in young women.
MRI classification and characterization of complex ovarian masses
Leydig cell tumors contain large, polygonal cells with abundant, occasionally vacuolated cytoplasm, and they are arranged in irregular acini.
Bilateral malignant seminomas in two unrelated, aged trumpeter hornbills (Bycanistes buccinator)

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