Leydig cell tumor


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Related to Leydig cell tumor: Leydig cells, interstitial cell tumor

Ley·dig cell tumor

(lī'dig),
a testicular and, less commonly, ovarian neoplasm composed of Leydig cells, usually benign but may be malignant; may secrete androgens or estrogens.

Leydig cell tumor

a generally benign neoplasm of interstitial cells of a testis that may cause gynecomastia in adults and precocious sexual development if the lesion occurs before puberty. The tumor is usually a circumscribed lobulated palpable mass.
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Leydig cell tumor

Ley·dig cell tu·mor

(lī'dig sel tū'mŏr)
A testicular and, less commonly, ovarian neoplasm composed of Leydig cells, usually benign but may be malignant; may secrete androgens or estrogens. Causes gynecomastia in adults and precocious sexual development in prepubescents.
References in periodicals archive ?
Type of Benign tumor years years years years 1 Mature cystic teratoma 05 03 02 2 Serous Cystadenoma 03 03 11 04 3 Papillary cystadenofibroma 02 4 Sertoli leydig cell tumor 01 5 Mucinous cystadenoma 03 6 Total 06 11 14 06 Age groups 51-60 >60 Sl no.
b) SF-1 is a good marker for steroidogenic tumors, including Leydig cell tumors and Sertoli cell tumors, and it shows negativity in all GCTs; however, there is no published data on its expression in the other SCSTs.
Leydig cell tumors, not otherwise specified steroid cell tumors, not otherwise specified (NOS)
Virilizing stromal Leydig cell tumor of the ovary in pregnancy-A Case Report.
Leydig cell tumor differs from Leydig cell hyperplasia by being solitary, whereas nodular Leydig cell hyperplasia is characteristically multifocal.
Leydig cell tumor of the testis associated with Klinefelter's syndrome and Osgood-Schlatter disease.
125) Most Leydig cell tumors, but only a minority of Sertoli cell tumors, are positive for [alpha]-inhibin and calretinin.
In contrast, germ cell tumors are rarely (at most) observed in rodents, whereas spontaneous Leydig cell tumors are extremely common in the F344/N rat.
Normal Leydig cells and spermatogonia of canine testicles express c-Kit in their cytoplasm, and canine Leydig cell tumors express positive immunolabeling for c-Kit, whereas c-Kit labeling is negative for Sertoli cell tumors.
For example, the F344/N rat typically used by the NTP has high background incidences of testicular Leydig cell tumors and mononuclear cell leukemia, along with unresolved issues about declining fertility, sporadic seizures, and chylothorax (accumulation of lymphatic fluid in the pleural cavity, which can result from lymphoma).
This group is composed of a variety of tumors including fibroma fibrothecoma, cystadenofibroma, Sertoli-and Leydig cell tumors.
Half of these animals were infertile and had larger testes and a significantly increased incidence of Leydig cell tumors in testes.