Leydig cell tumor


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Related to Leydig cell tumor: Leydig cells, interstitial cell tumor

Ley·dig cell tumor

(lī'dig),
a testicular and, less commonly, ovarian neoplasm composed of Leydig cells, usually benign but may be malignant; may secrete androgens or estrogens.

Ley·dig cell tu·mor

(lī'dig sel tū'mŏr)
A testicular and, less commonly, ovarian neoplasm composed of Leydig cells, usually benign but may be malignant; may secrete androgens or estrogens. Causes gynecomastia in adults and precocious sexual development in prepubescents.
References in periodicals archive ?
Primary tumors of the testes, such as Leydig cell tumors, can also serve as uncommon reason for gynecomastia.
The expression of EG-VEGF, both at mRNA and protein level, was restricted to the Leydig cell tumors [80].
The rare diagnosis of a synchronous Leydig cell tumor and seminoma can be made but it is important to distinguish these tumors from one another and from other malignancies due to different treatment strategies, especially in the event of recurrence.
(5,8) Granulosa cell tumor was the most common tumor (75%) observed in this group with one case of sertoli leydig cell tumor.
* Leydig cell tumors, not otherwise specified steroid cell tumors, not otherwise specified (NOS)
Virilizing stromal Leydig cell tumor of the ovary in pregnancy-A Case Report.
(b) SF-1 is a good marker for steroidogenic tumors, including Leydig cell tumors and Sertoli cell tumors, and it shows negativity in all GCTs; however, there is no published data on its expression in the other SCSTs.
Leydig cell tumor differs from Leydig cell hyperplasia by being solitary, whereas nodular Leydig cell hyperplasia is characteristically multifocal.
Leydig cell tumor of the testis associated with Klinefelter's syndrome and Osgood-Schlatter disease.
This report shows the presence of epigenetic control of NIS expression in Leydig cell tumors (14).
Sertoli-stromal tumors, also known as Leydig cell tumors, are rare, androgen-secreting, virilizing tumors in young women.
Leydig cell tumors contain large, polygonal cells with abundant, occasionally vacuolated cytoplasm, and they are arranged in irregular acini.