Leydig cell tumor


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Related to Leydig cell tumor: Leydig cells, interstitial cell tumor

Ley·dig cell tumor

(lī'dig),
a testicular and, less commonly, ovarian neoplasm composed of Leydig cells, usually benign but may be malignant; may secrete androgens or estrogens.

Leydig cell tumor

a generally benign neoplasm of interstitial cells of a testis that may cause gynecomastia in adults and precocious sexual development if the lesion occurs before puberty. The tumor is usually a circumscribed lobulated palpable mass.
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Leydig cell tumor

Ley·dig cell tu·mor

(lī'dig sel tū'mŏr)
A testicular and, less commonly, ovarian neoplasm composed of Leydig cells, usually benign but may be malignant; may secrete androgens or estrogens. Causes gynecomastia in adults and precocious sexual development in prepubescents.
References in periodicals archive ?
Leydig cell tumor of the testis is a rare, benign, interstitial tumor of the sex cord-stromal category.
Clinically occult Leydig cell tumor presenting with gynecomastia.
One juvenile granulosa cell tumor, 5 Leydig cell tumors, and 3 Sertoli-Leydig cell tumors were also tested for the same mutation for comparison.
Differences in response to LH between the rat and human may partially explain the greater sensitivity of rats to develop Leydig cell tumors compared with that in humans.
In a 2-year rat study, 31 mg/kg bw flusilazole induced Leydig cell tumors of the testis; flusilazole was fetotoxic and embryotoxic at [greater than or equal to] 9 mg/kg bw in a developmental study.
50] Melan-A immunoreactivity has been detected in melanocytes; however, Melan-A has also been detected in adrenocortical tumors and in other steroid tumors, including Sertoli-Leydig cell tumors and Leydig cell tumors.
Leydig cell tumors contain large, polygonal cells with abundant, occasionally vacuolated cytoplasm, and they are arranged in irregular acini.
This group is composed of a variety of tumors including fibroma fibrothecoma, cystadenofibroma, Sertoli-and Leydig cell tumors.