Leydig cell adenoma

Leydig cell adenoma

A benign circumscribed nodule of autonomously hyperfunctioning hyperplastic Leydig cells.

Aetiology
Activating mutation of LH receptor gene.
 
Clinical findings
Precocious puberty.
 
Management
Orchidectomy.

Leydig,

Franz von, German anatomist, 1821-1908.
Leydig cell adenoma - small benign tumors of the testis that often produce testosterone, causing endocrine symptoms. Synonym(s): interstitial cell tumor of testis
Leydig cells - cells between the seminiferous tubules of the testis that secrete testosterone. Synonym(s): interstitial cells
Leydig drain
Leydig duct - embryonic duct which becomes ductus deferens in males.
References in periodicals archive ?
05) increase in the incidence of testicular Leydig cell adenomas was observed at a dose of 250 mg/kg/day (228 times the human exposure).