Lewy body

(redirected from Lewy body disease)

Lewy body

(loo-wē)
[Frederic H. Lewy, Ger. neurologist, 1885–1950]
A neuronal cell with pigmented inclusion bodies. They are found in the brain in the substantia nigra and locus ceruleus, esp. in patients with a unique form of dementia with some Parkinsonian features, known as "dementia with Lewy bodies."
References in periodicals archive ?
The Mrs Doubtfire actor tragically killed himself in 2014 and it later emerged that he was suffering from Lewy body disease, which his wife attributed to his suicide.
Athletes who play contact sports associated with repetitive head impacts, such as football and ice hockey, may be at increased risk for Lewy body disease, which can cause Parkinson's, a brain disorder that leads to impaired movement and thinking, according to a study by researchers at the VA Boston (Mass.) Healthcare System and Boston University School of Medicine.
Saving Ted Turner: Is Lewy body disease in dementia treatable?
Williams received the "Commitment to Cures Award" from American Brain Foundation, honoring work she's done raising awareness for Lewy body disease since her husband's death.
Molano et al .[70] reported that iRBD patients who met MCI criteria subsequently developed autopsy-proven Lewy body disease. It was suggested that RBD patients with MCI predicted a high risk for developing DLB.[51] DLB always has cognitive decline, RBD, and visual hallucinations or fluctuations.[71] DLB patients with RBD exhibited more severe hypometabolism in the frontal regions, precuneus, superior parietal lobule, rolandic operculum, and amygdala, compared to those without RBD.[72]
The study published in New England Journal of Medicine, showed that repetitive head impacts from contact sports and other exposures are associated with motor symptoms including tremors, slowness and difficulty walking and are caused by Lewy Body Disease.
Williams suffered from dementia caused by Lewy body disease and killed himself in August 2014 at age 63.
He had been diagnosed with Parkinson's but an autopsy showed he actually had Lewy body disease, a brain condition which causes dementia.
(2,3) Among the common dementia-related diseases, cerebrovascular, (4) Alzheimer disease (AD), and Lewy body disease (LBD) pathologies exert well-known effects on cognitive function.
Williams suffered from dementia caused by Lewy body disease and took his own life in August 2014.
The essay published Thursday in the (http://www.neurology.org/content/87/13/1308.full) journal Neurology is the latest step in Schneider Williams' efforts to bring awareness to Lewy Body Disease (LBD) which led to the comedian's death in 2014.
Lon White and colleagues asked the question: 'What is the cause of dementia in older people?'They found in their subjects from the Honolulu Aging Study and the Nun Study (average age 88 and 90 years, respectively) that an individual's dementia is the result of multiple pathologies, including Alzheimer's, vascular disease, Lewy body disease, and hippocampal sclerosis, rather than a single cause.