Lewy body

(redirected from Lewy body disease)

Lewy body

(loo-wē)
[Frederic H. Lewy, Ger. neurologist, 1885–1950]
A neuronal cell with pigmented inclusion bodies. They are found in the brain in the substantia nigra and locus ceruleus, esp. in patients with a unique form of dementia with some Parkinsonian features, known as "dementia with Lewy bodies."
References in periodicals archive ?
Having retired to Notting Hill, London, Johnny Keating died in Chiswick Nursing Centre after suffering from Lewy Body Disease (LBD, a form of dementia).
Diagnosed with Alzheimer's disease in 2011 and Lewy Body Disease, it eventually brought him home to his native Shrewsbury to be closer to family and friends and more attention to his health.
Doctors commonly focus on common disorders such as cerebrovascular disease, Alzheimer's disease, and Lewy body disease when evaluating patients with cognitive decline.
Casey, 82, who presented the American Top 40 and provided the voice of Shaggy in Scooby Doo, suffers from Lewy body disease - a form of dementia which has left him unable to move.
Part III presents a few chapters on monocyte-macrophage differentiation and T lymphocytes, while part IV addresses a range of general disease-related topics including sepsis, lysosomal degradation, cancer sensitization, biliary cirrhosis, cardiovascular disease, fatty liver disease, UV radiation resistance, Huntingtin protein degradation, and Lewy body disease.
Lewy body disease results from the damage caused by progressive spread of Lewy bodies and Lewy neurites to specific parts of the brain (Love, 2005; Yokota et al, 2007).
The recent National Institute on Aging-Alzheimer's Association (NIA-AA) revision of criteria for the pathologic diagnosis of AD recommends a minimum of 13 histologic sections to evaluate for Alzheimer disease neuropathologic change (ADNC), Lewy body disease (LBD), vascular brain injury, microvascular lesions, and hippocampal sclerosis.
FDGPET abnormalities in nonamnesiac MCI ranged from normal metabolism to patterns resembling frontotemporal dementia and diffuse Lewy body disease, suggesting another dimension to the spectrum of AD.
Much more is known about dementia resulting from Lewy Body disease, and also about Pick's disease and other frontotemporal dementias.
These may be due to age-related decline in dopaminergic activity, incidental Lewy body disease, degenerative pathologies (early PD and Alzheimer's disease) or vascular pathology.
Horvath of Eugene, who died May 21 of Lewy body disease.