FUT3

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FUT3

A gene on chromosome 19q13.3 that encodes a fucosyltransferase with alpha(1,3)-fucosyltransferase and alpha(1,4)-fucosyltransferase activities, which catalyses the addition of fucose to precursor polysaccharides in the last step of Lewis antigen biosynthesis. 

Molecular pathology
FUT3 mutations are responsible for most Lewis antigen-negative blood group phenotypes.
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