leukocidin

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leukocidin

 [loo″ko-si´din]
1. a substance toxic to leukocytes, killing the cells with or without lysis.
2. a type of exotoxin produced by pathogenic bacteria such as staphylococci or streptococci; it destroys leukocytes and may also damage monocytes and macrophages.

leu·ko·ci·din

(lū'kō-sī'din, lū-kō-sī'din),
A heat-labile substance that is elaborated by many strains of Staphylococcus aureus, Streptococcus pyogenes, and pneumococci and manifests a destructive action on leukocytes, with or without lysis of the cells.
[leukocyte + L. caedo, to kill]

leukocidin

/leu·ko·ci·din/ (-si´din) a substance produced by some pathogenic bacteria that is toxic to polymorphonuclear leukocytes (neutrophils).

leukocidin

(1) An antibody which lyses white cells following complement fixation.
(2) A pore-forming cytotoxin produced by certain bacteria.

leu·ko·ci·din

(lū'kō-sī'din)
A heat-labile substance that is elaborated by many strains of Staphylococcus aureus, Streptococcus pyogenes, and pneumococci; manifests a destructive action on leukocytes, with or without lysis of the cells.
Synonym(s): leucocidin.
[leukocyte + L. caedo, to kill]

leukocidin

a substance produced by some pathogenic bacteria that is toxic to polymorphonuclear leukocytes (neutrophils).
References in periodicals archive ?
Severe community-onset pneumonia in healthy adults caused by methicillin-resistant Staphylococcus aureus carrying the Panton-Valentine leukocidin genes.
Novel multiplex PCR assay for detection of the staphylococcal virulence marker Panton-Valentine leukocidin genes and simultaneous discrimination of methicillin-susceptible from-resistant staphylococci.
Contribution of Panton-Valentine leukocidin in community-associated methicillin-resistant Staphylococcus aureus pathogenesis.
Community-acquired methicillin-resistant Staphylococcus aureus: the role of Panton-Valentine leukocidin.
Effect of antibiotics on Staphylococcus aureus producing Panton-Valentine leukocidin.
In addition, 10 of 20 CA-MRSA isolates tested positive for the Panton-Valentine leukocidin (PVL) gene, which code for a known CA-SA virulence factor.
Community-acquired methicillin- resistant Staphylococcus aureus carrying Panton-Valentine leukocidin genes: worldwide emergence.
Identification of staphylococcal Panton-Valentine leukocidin as a potent dermonecrotic toxin.
Staphylococcus aureus Panton-Valentine leukocidin causes necrotizing pneumonia.
Is Panton-Valentine leukocidin the major virulence determinant in community-associated methicillin-resistant Staphylococcus aureus disease?
designation [6]), but also that of the locus for the Panton-Valentine leukocidin (PVL).
In addition, 112 isolates harbored the related lukE-lukD genes of another leukocidin frequently recovered from patients with all types of staphylococcal infections (3).