leukoplakia

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Related to Leucoplakia: leukoplakia vulvae

leukoplakia

 [loo″ko-pla´ke-ah]
a disease marked by the development of white thickened patches on the mucous membranes of the cheeks (leukoplakia buccalis), gums, or tongue (leukoplakia lingualis); the patches sometimes form fissures and often become malignant. They may grow into larger patches or form ulcers. Those in the mouth may in time cause pain during swallowing of food or speaking. Leukoplakia affects mostly middle-aged to elderly men, often after prolonged irritation of the mouth from such varying factors as badly fitting dentures or immoderate use of tobacco.

Treatment is aimed at removing any possible cause of physical or chemical irritation; the patient should give up tobacco and possibly also alcohol and extremely hot food. Dental attention may be necessary if teeth are uneven or dentures do not fit properly. Surgical removal of the affected area is relatively simple and may be the best means of preventing further development of the condition.
oral hairy leukoplakia a white filiform to flat patch occurring on the tongue or, rarely, on the buccal mucosa, caused by infection with Epstein-Barr virus and associated with human immunodeficiency virus infection.
leukoplakia vul´vae the presence of hypertrophic grayish-white infiltrated patches on the vulvar mucosa; specific diagnosis is determined by biopsy.

leu·ko·pla·ki·a

(lū'kō-plā'kē-ă),
A white patch of oral or female genital mucous membrane that cannot be wiped off and cannot be diagnosed clinically as any specific disease entity; in current usage, a clinical term without histologic connotation.
Synonym(s): smoker's patches
[leuko- + G. plax, plate]

leukoplakia

(lo͞o′kə-plā′kē-ə) also

leucoplakia

(lo͞o′kə-plā′kē-ə)
n.
An abnormal condition characterized by white spots or patches on mucous membranes, especially of the mouth and vulva. Also called leukoplasia.

leukoplakia (vulvar)

Chronic vulvar dystrophy, see there.  

The term leukoplakia continues to be widely used (incorrectly) in the working gynaecological parlance; the error lies in that the term leukoplakia merely refers to the macroscopic appearance of white patches in the postmenopausal vulva, which most commonly correspond to hyper- or parakeratosis and far less commonly to carcinoma in situ or Paget's disease. The portent of vulvar leukoplakia is thus in sharp contrast to oral leukoplakia, which is generally regarded as a pre-malignant lesion.

leukoplakia

A potentially precancerous white patch or plaque on a mucosa characterized by epithelial hyperplasia and hyperkeratosis, often caused by chronic irritation; leukoplakia–LP affects the mucosa of oral cavity, upper respiratory tract, vulva, uterine cervix, renal pelvis, urinary bladder; in each site, the significance differs ENT Smoker's keratosis A white plaque or patch on the oral mucosa. See Hairy leukoplakia Ob/Gyn A white plaque or patch on the vaginal mucosa, seen without magnification or acetic acid, and often elevated from surrounding surfaces with a sharp border and Lugol's non-staining Histology Hyperkeratosis, possibly epithelial proliferation. See Speckled leukoplakia.

leu·ko·pla·ki·a

(lū'kō-plā'kē-ă)
A white patch of oral mucous membrane that cannot be wiped off and cannot be diagnosed clinically; the spots are smooth, irregular in size and shape, hard, and occasionally fissured. Often associated with pipe smoking. Biopsy may show malignant or premalignant changes.
Synonym(s): leucoplakia.
[leuko- + G. plax, plate]

leukoplakia

(loo?ko-pla'ke-a) [ leuko- + Gr. plax, plate + -ia]
Enlarge picture
LEUKOPLAKIA
Formation of white spots or patches on the mucous membrane of the tongue or cheek. The spots are smooth, irregular in size and shape, hard, and occasionally fissured. The lesions may become malignant. Synonym: leukokoria; leukoplasia; smoker's tongue See: illustration

leukoplakia buccalis

Leukoplakia of the mucosa of the cheek.
Enlarge picture
ORAL HAIRY LEUKOPLAKIA

oral hairy leukoplakia

Leukoplakia of the tongue. It is typically found in immunocompromised patients is a result of Epstein-Barr virus infection.
illustration

leukoplakia vulvae

Lichen sclerosis et atrophicus.

leukoplakia

A thickened white patch occurring on a mucous membrane, especially inside the mouth, on the lips or on the female genitalia. Leukoplakia is a response to long-term irritation and is a PRECANCEROUS condition that should never be ignored.

leu·ko·pla·ki·a

(lū'kō-plā'kē-ă)
White patch of oral or female genital mucous membrane that cannot be wiped off and cannot be diagnosed clinically as any specific disease entity; in current usage, no histologic connotation.
Synonym(s): leucoplakia.
[leuko- + G. plax, plate]
References in periodicals archive ?
[1] Among malignant tumours squamous cell carcinomas were recorded higher in number, whereas premalignant leucoplakia were the common presentation the reason being high number of malignant cases.
[11] A total of 340 cases in our study had shown the presence of precancerous lesions and conditions amongst which leucoplakia was the commonest precancerous lesion and OSMF was clinically the predominant precancerous condition in our survey.
Estimation and comparative evaluation of serum iron, copper, zinc, and copper/zinc ratio in oral leucoplakia, submucous fibrosis, and squamous cell carcinoma.
The other viral infections seen were herpes zoster, molluscum contagiosum and oral hairy leucoplakia.
Pre-malignant lesions like Leucoplakia, Erythroplakia, Submucosal fibrosis, Moles, Lichen planus, Pigmentations, Giant aphthous ulcers, Sharp dental margin ulcers, ulcers of Tuberculosis, syphilis and other granulomatous lesions were excluded from the study.
Among the Opportunistic Infections (OIs) tuberculosis was the commonest 40(38%) cases including extra pulmonary tuberculosis contributing 16(15%) cases followed by oral candidiasis 22(21%), cryptococcal meningitis1 5(14%), herpes zoster14(14%), penicillium marneffei 5(5%),cerebral toxoplasmosis 5(5%), cryptosporidial diarrhoea 4(4%), pneumocystis carinii pneumonia (PCP) 3(3%),viral meningitis 2(2%), Kaposi's Sarcoma 1(1%), hairy cell leucoplakia 1(1%) respectively [Table-4].
In oral manifestation, candidiasis were most common followed by pigmentation, aphthous ulcers, herpes labialis, oral hairy leucoplakia which were seen with CD4 count < 200 cells/ cumm.
In case of leucoplakia, 41.9% of the current tobacco users and only 3.4% of non users of tobacco had leucoplakia with odds ratio of 20.5 which was found to be statistically significant (p<0.001).