Leser-Trelat sign


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Le·ser-Tré·lat sign

(lā'zā trā'lah),
the sudden appearance and rapid increase in the number and size of seborrheic keratoses with pruritus; associated with internal malignancy.

Leser-Trélat sign

[lā′zər trālä′]
Etymology: Edmund Leser, German surgeon, 1828-1916; Ulysse Trélat, French surgeon, 1828-1890
a condition of malignant cells present in the skin, characterized by the sudden onset of multiple seborrheic keratoses, with pruritus or enlargement of preexisting keratosis in older adults. It is associated with adenocarcinoma of the stomach, breast cancer, and lung cancer.

Leser,

Edmund, German surgeon, 1828-1916.
Leser-Trélat sign - the sudden appearance and rapid increase in the number and size of seborrheic keratoses with pruritus, associated with internal malignancy.

Trélat,

Ulysse, French surgeon, 1828-1890.
Leser-Trélat sign - see under Leser
Trélat stools - stools streaked with blood, occurring in proctitis.
References in periodicals archive ?
Till date there is only one report of Leser-Trelat sign with associated carcinoma of breast.
in their report of Leser-Trelat sign in mother and daughter with breast cancer observed that in their both patients there was sudden appearance of seborrheic keratoses with increased number and s ze after mastectomy and the lesions remains stable long after mastectomy.
Till date there is only one report of Leser-Trelat sign associated with carcinoma of breast in which skin lesions did not progress or regress after mastectomy.
Bile duct adenocarcinoma with Leser-Trelat sign and pure red blood cell aplasia.
The Leser-Trelat sign A useful predictor of neoplasms in clinic?
The leser-trelat sign in association with carcinoma of the ampulla of Vater.
Leser-Trelat sign with porphyria cutanea tarda and malignant hepatoma.
Post-renal transplantation Leser-Trelat sign associated with carcinoma of the gallbladder: a rare association.
Leser-Trelat sign associated with leiomyosarcoma of the stomach.
Bilateral Leser-Trelat sign mirroring lung adenocarcinoma with early metastases to the contralateral lung.
The Leser-Trelat sign is associated with nasopharyngeal carcinoma: case report and review of cases reported in China.
Small cell carcinoma of the lung with Leser-Trelat sign.