Any case of sudden, extensive seborrheic keratosis is suspected to be a Leser-Trelat sign
, which is known to be associated with human immunodeficiency virus or underlying malignancy--especially in the gastrointestinal system.
Till date there is only one report of Leser-Trelat sign with associated carcinoma of breast.
in their report of Leser-Trelat sign in mother and daughter with breast cancer observed that in their both patients there was sudden appearance of seborrheic keratoses with increased number and s ze after mastectomy and the lesions remains stable long after mastectomy.3Li et al, in their report of Leser-Trelat sign with primary hepatic carcinoma found that at 6-month postoperative follow-up, the lesions of seborrheic keratoses stopped progressing, but did not regress.
Till date there is only one report of Leser-Trelat sign associated with carcinoma of breast in which skin lesions did not progress or regress after mastectomy.
Bile duct adenocarcinoma with Leser-Trelat sign and pure red blood cell aplasia.
The Leser-Trelat sign A useful predictor of neoplasms in clinic?
Leser-Trelat sign associated with carcinoma of gastro-esophageal junction.
The leser-trelat sign in association with carcinoma of the ampulla of Vater.
Leser-Trelat sign with porphyria cutanea tarda and malignant hepatoma.
Post-renal transplantation Leser-Trelat sign associated with carcinoma of the gallbladder: a rare association.
Leser-Trelat sign associated with leiomyosarcoma of the stomach.
Bilateral Leser-Trelat sign mirroring lung adenocarcinoma with early metastases to the contralateral lung.