lentigo maligna


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lentigo

 [len-ti´go] (L.)
a flat, brownish pigmented spot on the skin due to increased deposition of melanin and an increased number of melanocytes; a freckle. (See Atlas 2, Part O.)
lentigo malig´na (malignant lentigo) see lentigo maligna melanoma.
senile lentigo (lentigo seni´lis,) (solar lentigo) a small smooth round brownish patch appearing on the face, neck, or back of the hands of many older people, caused by an increase in pigment; these are entirely harmless. Although these spots are associated with aging, it is not age that is the principal cause but many years of exposure to sun and wind. Called also liver spot.

len·ti·go ma·lig·na

a brown or black mottled, irregularly outlined, slowly enlarging lesion resembling a lentigo in which there are increased numbers of scattered atypical melanocytes in the epidermis, usually occurring on the face of older persons; after many years the dermis may be invaded and the lesion is then termed lentigo maligna melanoma.

lentigo maligna

Hutchinson's melanotic freckle, lentigo maligna melanoma
A lesion comprising 10% of melanomas, affects those > age 60; flat, indolent, arises in premalignant freckle, located on sun-exposed aging skin; begins as an unevenly pigmented macule with an irregular border, slowly extends peripherally Etiology Solar overexposure,13 progress to melanoma in 10-15 yrs Prognosis > 95% 5-yr survival. See Lentigo, Melanoma.

len·ti·go ma·lig·na

(len-tī'gō mă-lig'nă)
A brown or black mottled, irregularly outlined, slowly enlarging lesion resembling a lentigo in which there are increased numbers of scattered atypical melanocytes in the epidermis, usually occurring on the face of older persons; after many years the dermis may be invaded and the lesion is then termed lentigo maligna melanoma.
Synonym(s): Hutchinson freckle.
Enlarge picture
LENTIGO MALIGNA: SOURCE: Centers for Disease Control and Prevention; Carl Washington, MD

lentigo maligna

A pigmented lesion of the skin in which a large number of superficial, atypical melanocytes are found. Synonym: Hutchinson's freckle
See: illustration
See also: lentigo

Hutchinson,

Sir Jonathan, English surgeon and pathologist, 1828-1913.
Hutchinson crescentic notch - the semilunar notch on the incisal edge of Hutchinson teeth, encountered in congenital syphilis.
Hutchinson disease - age-related guttate choroiditis.
Hutchinson facies - the peculiar facial expression produced by drooping eyelids and motionless eyes in external ophthalmoplegia.
Hutchinson freckle - a brown or black mottled, irregularly outlined, slowly enlarging lesion. Synonym(s): lentigo maligna
Hutchinson mask - the sensation experienced in tabetic neurosyphilis as if the face were covered with a mask or with cobwebs.
Hutchinson patch - interstitial or parenchymatous keratitis giving rise to neovascularization of the cornea. Synonym(s): salmon patch
Hutchinson pupil - dilation of the pupil on the side of the lesion as part of a third nerve palsy.
Hutchinson teeth - the teeth of congenital syphilis in which the incisal edge is notched and narrower than the cervical area. Synonym(s): notched teeth; screwdriver teeth; syphilitic teeth
Hutchinson triad - parenchymatous keratitis, labyrinthine disease, and Hutchinson teeth, significant of congenital syphilis.
Hutchinson-Gilford disease - a condition in which normal development in the first year is followed by gross retardation of growth, with dry wrinkled skin, total alopecia, and birdlike facies. Synonym(s): Hutchinson-Gilford syndrome; progeria
Hutchinson-Gilford syndrome - Synonym(s): Hutchinson-Gilford disease
References in periodicals archive ?
Lentigo maligna: melanoma in situ on chronically sundamaged skin.
Some units have a special Lentigo Maligna Clinic with all the treating specialists and the patient present.
(3-8,16) Historically, three main subtypes of melanoma including superficial spreading melanoma (SSM), lentigo maligna melanoma (LMM) and nodular melanoma (NM) were first described in 1969; (9) desmoplastic melanoma (DM) was added in 1971; (12) and acral lentiginous melanoma (ALM) was introduced in 197710 and defined in 1980.
Atipik, pigmente, makuler lezyonlarda histolojik tani , solar lentigodan in-situ melanoma (lentigo maligna pattern) veya invazive melanomaya {lentigo maligna melanoma) kadar genis araliga sahiptir.
This early form, known as LM, precedes the more invasive form, lentigo maligna melanoma (LMM), and the progression of LM to LMM typically occurs after 10 to 15 years.
The most common specific histologic diagnosis reported was melanoma in situ (22.3%) followed by lentigo maligna (9.3%), nodular melanoma (5.6%), superficial spreading melanoma (5.3%), lentigo maligna melanoma (4.7%), and acral lentiginous melanoma (4.6%).
Lentigo maligna melanoma is less common than the other two types of melanoma; this type is usually seen in older people.
(1.) Cohen LM, Lentigo maligna and lentigo maligna melanoma.
The sensitivity numerator included the total number of malignant lesions (malignant melanoma, lentigo maligna, squamous cell carcinoma, and basal cell carcinoma) and severely atypical lesions (nevi with severe atypia) that RCM diagnosis recommended for excision.
"Mohs micrographic surgery and other staged excision techniques can provide exhaustive peripheral margin histologic assessment for melanoma in situ, lentigo maligna type, and tissue sparing in anatomically constrained sites," Dr.
Mustarde flap lower eyelid reconstruction following lentigo maligna excision.