Lennox-Gastaut syndrome

(redirected from Lennox gastaut)

Len·nox-Gas·taut syn·drome

(len'ŏks gahs-tō),
a generalized myoclonic astatic epilepsy in children, with mental retardation, resulting from various cerebral afflictions such as perinatal hypoxia, cerebral hemorrhage, encephalitides, and maldevelopment or metabolic disorders of the brain; characterized by multiple seizure types (generalized tonic, atonic, myoclonic, tonic-clonic, and atypical absence) and background slowing and slow spike and wave pattern on EEG.
Synonym(s): Lennox syndrome

Lennox-Gastaut syndrome

[len′oks-gästō′]
Etymology: William G. Lennox, American neurologist, 1884-1960; Henri Gastaut, French biologist, b. 1914
a condition in which a variety of generalized seizures, such as tonic, atonic, absence, tonic-clonic, akinetic, and myoclonic, begin to appear in the first 5 years of life. Seizures are often intractable and may require multiple antiepileptic medications. Mental retardation is often present. Among suggested causes are inherited metabolic abnormalities and perinatal or postnatal disorders. Also called Gastaut's disease.

Lennox-Gastaut syndrome

Lennox syndrome Neurology A severe encephalopathic form of epilepsy that constitutes 5% of all childhood epilepsies Clinical Early onset of multiple types–eg, absence, atonic, and others of seizures, slow spike-wave EEG pattern, cerebral atrophy, and often progressive mental retardation; seizures are poorly controlled even with multiple anticonvulsants Prognosis For cognitive development, poor; felbamate may ↓ Sx. See Felbamate.

Len·nox-Gas·taut syn·drome

, Lennox syndrome (len'ŏks gahs-tō' sin'drōm)
A generalized myoclonic astatic epilepsy in children, with mental retardation, resulting from various cerebral afflictions such as perinatal hypoxia, cerebral hemorrhage, encephalitides, maldevelopment or metabolic disorders of the brain; characterized by multiple seizure types (generalized tonic, atonic, myoclonic, tonic-clonic, and atypical absence) and background slowing and slow spike and wave pattern on electroencephalogram; patients are usually mentally retarded or developmentally delayed.

Gastaut,

Henri, French biologist, 1915–.
Gastaut syndrome - juvenile hemiplegic epilepsy with ipsilateral signs.
Lennox-Gastaut syndrome - see under Lennox

Lennox,

William G., U.S. neurologist, 1884-1960.
Lennox-Gastaut syndrome - a generalized myoclonic astatic epilepsy in children, with mental retardation. Synonym(s): Lennox syndrome
Lennox syndrome - Synonym(s): Lennox-Gastaut syndrome
References in periodicals archive ?
Her seizures started at the age of six months and three months later she was diagnosed with Lennox Gastaut.
Bailey Williams, 12, tried 15 drugs, with side effects including tremors and hair loss, before doctors diagnosed Lennox Gastaut Syndrome, a rare form of drug resistant epilepsy.
Mum-of-two Mary is a full-time carer to her daughter Elizabeth, 33, who has Lennox Gastaut Syndrome, a severe form of epilepsy.
Karina has Lennox Gastaut Syndrome, which means she suffers from seizures and she also has autism.
It is also indicated as adjunctive therapy for adults and children (aged 2 and above) with partial onset seizures or generalized tonic-clonic seizures, and in adults and children as adjunctive therapy for the treatment of seizures associated with Lennox Gastaut syndrome.
The youngster suffers from Lennox Gastaut Syndrome, a rare form of epilepsy which affects only about 400 people in Britain.
Bailey has Lennox Gastaut Syndrome, which is a severe form of epilepsy.
It also is indicated as adjunctive therapy for adults and children (aged 2 and above) with partial onset seizures or generalized tonic-clonic seizures, and in adults and children as adjunctive therapy for the treatment of seizures associated with Lennox Gastaut syndrome.
Lamictal received approval earlier this year for add-on therapy for generalized seizures in Lennox Gastaut syndrome (LGS).