Leishmania braziliensis

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Related to Leishmania braziliensis: Leishmania donovani, Leishmania mexicana, Leishmania tropica


a genus of protozoa comprising parasites of worldwide distribution, several species of which are pathogenic for humans. All species are morphologically indistinguishable, and therefore the organisms have usually been assigned to species and subspecies according to their geographic origin, the clinical syndrome they produce, and their ecologic characteristics. They have also been separated based on their tendency to cause visceral, cutaneous, or mucocutaneous leishmaniasis. In some classifications, Leishmania is grouped in four complexes comprising species and subspecies: L. donovani, L. tropica, L. mexicana, and L. viannia.
Life cycle of Leishmania. From Mahon and Manuselis, 2000.
Leishmania brazilien´sis Leishmania viannia.
Leishmania donova´ni donova´ni a subspecies of the L. donovani complex causing the classic form of visceral leishmaniasis in India. It is transmitted by the sandfly Phlebotomus argentipes, with humans being the only major reservoir hosts. Called also L. donovani.
Leishmania ma´jor a species of the L. tropica complex, transmitted by Phlebotomus papatasi, causing the rural form of Old World cutaneous leishmaniasis. Called also L. tropica major.
Leishmania mexica´na a complex comprising the species and subspecies causing the New World form of cutaneous leishmaniasis in humans: L. m. mexicana, L. m. amazonensis, and L. pifanoi.
Leishmania tro´pica
1. a complex comprising the species causing the Old World form of cutaneous leishmaniasis: L. tropica, L. major, and L. aethiopica.
2. a species of the L. tropica complex causing the urban form of Old World cutaneous leishmaniasis. It is found in Iran, Iraq, and India, transmitted by Phlebotomus sergenti; and in southern France, Italy and certain Mediterranean islands, transmitted by P. papatasi. Human to human transmission may also occur.
Leishmania vian´nia a taxonomic complex comprising the subspecies that cause mucocutaneous leishmaniasis in its various forms; all of the subspecies develop in the midgut, foregut, and hindgut of their sandfly vectors. Formerly called L. braziliensis.

Leish·man·i·a bra·zil·i·en·'sis

a species that is the causal agent of mucocutaneous leishmaniasis, endemic in southern Mexico and Central and South America, and transmitted by various species of Lutzomyia (New World sandflies); forest rodents and other tropic arboreal animals serve as reservoir hosts. Leishmania braziliensis is currently divided into three clinically, epidemiologically, and biochemically distinct strains or subspecies: Leishmania b. braziliensis, Leishmania b. guyanensis, and Leishmania b. panamensis.

Leishmania braziliensis

The causative agent of American leishmaniasis.
See also: Leishmania
References in periodicals archive ?
Leishmania braziliensis amastigotes stimulate production of IL-1[beta], IL-6, IL-10 and TGF-p by peripheral blood mononuclear cells from nonendemic area healthy residents.
Detection of Leishmania braziliensis in naturaliy infected sandflies by the polymerase chain reaction.
DEFINICION: ADN mitocondrial del maxicirculo pre-editado de Leishmania braziliensis.
Palabras clave: Leishmania braziliensis peruviana, Lepidium peruvianum; Lepidium meyenii, actividad leishmanicida, plantas medicinales peruanas, ecotipos de Maca.
Among the many agents that have been used are pentavalent antimonials (which cause some systemic toxicity and are used to treat the mucocutaneous form), pentamidine, amphotericin B (which is used primarily for visceral leishmaniasis), paromomycin (used for the visceral and cutaneous forms), cytokines such as interferon gamma (used for some mucocutaneous forms, including those caused by Leishmania braziliensis strains), oral antifungals such as ketoconazole, fluconazole, and itraconazole (which are well tolerated), and hipoxanthine (which inhibits purine anabolism and slows Leishmania proliferation).
Umbratilis (en Amazonas, Boyaca y Caqueta), transmisor de leishmaniasis braziliensis guayanensis; Lu, ylephiletor (en Choco y Valle), vector de Leishmania braziliensis panamensis; Lu.
En el pais se han descrito 7 especies de flebotomos responsables de la transmision de la enfermedad; asi por ejemplo, a nivel del pie de monte andino, region Centro-Norte y Oriental se ha encontrado Lutzomyia panamensis, Lutzomyia ovallesi y Lutzomyia gomezi, asociadas a la transmision de Leishmania braziliensis [1, 2, 6, 12].
To test the specificity of the primers, reactions containing DNA from other isolated zoonotic protozoa, including Trypanosoma cruzi (amastigotes isolated from the cardiac muscle of a dog with acute Chagas disease), Leishmania amazonensis (MHOM/ BR/2009/26361P promastigotes isolated at Instituto Evandro Chagas), and Leishmania braziliensis (MHOM/BR/1999/17593P promastigotes isolated at Instituto Evandro Chagas), were included in the experiment as controls.
En cuanto a la especie hallada, Leishmania braziliensis, es dable destacar que es una de las mas frecuentemente identificadas en esta especie animal en Sudamerica, especialmente en Brasil (7).
Clinical presentations of Leishmania braziliensis braziliensis.
Isolation of Leishmania braziliensis from Lutzomyia ovallesi (Diptera:Psychodidae) in Guatemala.

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