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[Sir William Boog Leishman, Brit. medical officer, 1865–1926; Charles Donovan, Brit. bacteriologist, 1863–1951]
Nonflagellated trypanosomes found within the cytoplasm of cells infected by Leishmania donovani, the pathogen that causes visceral Leishmaniasis.Synonym: amastigote
Leishman-Donovan bodiesThe form in which Leishmania parasites appear in MACROPHAGE cells in LEISHMANIASIS. They appear as oval, nucleated, non-flagellated structures in the CYTOPLASM of the MACROPHAGES. Also known as amastigotes . (Major-General Sir William Boog Leishman, 1865–1926, English Army pathologist, and Lt Col Charles Donovan, 1863–1951, Irish physician).
round or oval bodies found in reticuloendothelial cells, especially those of the spleen and liver, in visceral leishmaniasis; they are amastigote intracellular stages of Leishmania donovani. The term is also used to designate similar forms of L. tropica found in macrophages in lesions of cutaneous leishmaniasis.