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Related to Leiomyomas: leiomyomata


a benign tumor derived from smooth muscle, most often of the uterus (leiomyoma uteri).
bizarre leiomyoma epithelioid leiomyoma.
leiomyoma cu´tis one arising from cutaneous or subcutaneous smooth muscle fibers, found singly or multiply, usually as lesions arising from arrectores pilorum muscles; it may also occur as a solitary genital lesion or a solitary angioleiomyoma arising from the muscle of veins.
epithelioid leiomyoma one in which the cells are polygonal rather than spindle shaped, usually found in the stomach. Called also bizarre leiomyoma and leiomyofibroma.
leiomyoma u´teri (uterine leiomyoma) leiomyoma of the uterus; called also uterine myoma and, colloquially, fibroids. It is the most common of all tumors found in women. It may occur in any part of the uterus, although it is most frequently in the body of the organ.

Leiomyomas usually occur during the third and fourth decades, and are often multiple, although a single tumor may occur. They are usually small but may grow quite large and occupy most of the uterine wall; after menopause, growth usually ceases. Symptoms vary according to the location and size of the tumors. As they grow they may cause pressure on neighboring organs, painful menstruation, profuse and irregular menstrual bleeding, vaginal discharge, or frequent urination, as well as enlargement of the uterus.

In pregnancy, the tumors may interfere with natural enlargement of the uterus with the growing fetus. They may also cause spontaneous abortion and death of the fetus.

Small leiomyomas are usually left undisturbed and are checked at frequent intervals. Larger tumors may be removed surgically, sometimes accompanied by a hysterectomy, or medication may be prescribed to induce a temporary menopause.
Leiomyoma of the uterus. The tumors may be subserosal, intramural, or submucosal. Subserosal and submucosal tumors may be pedunculated and may protrude from the uterine surface or into the uterine cavity, respectively. The stalk of pedunculated tumors may also become twisted. From Damjanov, 2000.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.


A benign neoplasm derived from smooth (nonstriated) muscle.
[leio- + G. mys, muscle, + -oma, tumor]
Farlex Partner Medical Dictionary © Farlex 2012


n. pl. leiomyo·mas or leiomyo·mata (-mə-tə)
A benign tumor derived from smooth muscle, occurring most often in the uterus.

lei′o·my·o′ma·tous (-ō′mə-təs, -ŏm′ə-) adj.
The American Heritage® Medical Dictionary Copyright © 2007, 2004 by Houghton Mifflin Company. Published by Houghton Mifflin Company. All rights reserved.


Fibroma, plural, leiomyomata or, incorrect, but increasingly popular, leiomyomas A benign, well-circumscribed smooth muscle tumor most common in the uterus and stomach. See Fibroid, Fibroma, Intestinal leiomyoma.
McGraw-Hill Concise Dictionary of Modern Medicine. © 2002 by The McGraw-Hill Companies, Inc.


A benign neoplasm derived from smooth (nonstriated) muscle.
[leio- + G. mys, muscle, + -oma, tumor]
Medical Dictionary for the Health Professions and Nursing © Farlex 2012


A benign tumour of smooth muscle found most commonly in the womb (uterus). Leiomyomas often contain much fibrous tissue. Also known as FIBROID, fibromyoma or leiomyofibroma.
Collins Dictionary of Medicine © Robert M. Youngson 2004, 2005


A benign tumor composed of muscle tissue. Leiomyomas in the uterus are sometimes called fibroids.
Mentioned in: Hysterosonography
Gale Encyclopedia of Medicine. Copyright 2008 The Gale Group, Inc. All rights reserved.


A benign neoplasm derived from smooth (nonstriated) muscle.
[leio- + G. mys, muscle, + -oma, tumor]
Medical Dictionary for the Dental Professions © Farlex 2012

Patient discussion about leiomyoma

Q. uterine fibroids. Whats the best way to deal with them? My doctor says hysterectomy? What about my hormones?

A. Yes, drugs that suppress the levels of the female sex hormones (estrogen) are successful for treating uterine fibroids. However, the relief is only temporary and the fibroids recur once the treatment is stopped. In addition, these treatments cause side effects similar to menopause.

Surgery is the definitive treatment, especially for complications such as bleeding or pain, and when there's a suspicion for malignancy.

You may read more here: http://www.nlm.nih.gov/medlineplus/ency/article/000914.htm

More discussions about leiomyoma
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References in periodicals archive ?
Uterine leiomyomas are highly common lesions of unclear etiology.
At 45 years of age, she underwent a total abdominal hysterectomy (TAH) at another hospital for a leiomyoma, which persisted after the surgery.
Leiomyomas of the round ligament can be a possible but rare etiology of the inguinal mass and can be mistaken for an inguinal hernia or lymphadenopathy.
BMI: Women with higher BMI were found to have increased risk of developing fibroids due to increase in biologically available estrogens; it occurs in two ways as the adipose tissue converts the adrenal and ovarian androgens into estrogens and several obesity related mechanisms lead to decreased synthesis of sex hormone binding globulin thus ultimately resulting in increased growth and prevalence of leiomyomas by estrogens.
Chinese herbal medicine Guizhi Fuling Formula for treatment of uterine leiomyomas: a systematic review of randomised clinical trials.
Angiomyoma (vascular leiomyoma): a clinicopathological study.
Further, immunohistochemical (IHC) staining showed strong reactivity for vimentin, smooth muscle actin (SMA), and desmin and a negative reaction against S.100 that favored a diagnosis of leiomyoma. IHC using antibodies directed against SMA and S.100 protein showed diffuse immunoreactivity for SMA and negative for S.100 [Figures 3 and 4].
Lack of CD34 positive stromal cells within angiomyomas (vascular leiomyomas).
(18) found a significant correlation between baseline ADC ADC between leiomyomas with VR greater than 50% versus less than 50% at 6-month follow-up (P = 0.07).
The resected nodule was diagnosed as a leiomyoma. The specimen didn't include adjacent normal skin or deep muscle tissue, but it is thought to have arisen from the arrector pili muscles considering its location (below the dermis and above the muscle).
Treatment of multiple cutaneous leiomyomas with CO2 laser ablation.
Leiomyomas which origin from smooth muscles are benign mesenchymal tumors (6,7,8).