Legionnaire's disease


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Legionnaire's disease

Legionella pneumonia Infectious disease A lung infection caused by Legionella pneumophila, which is either sporadic or epidemic with a mortality of up to 15%; depending on the population, Legionella spp cause 1–27% of CAPs; ♂:♀ ratio, 3:1 Epidemiology Most
L pneumophila infections are associated with buildings and ventilation systems; most epidemics occur during the summer with 0.5 to 5% attack rates; the only documented mode of spead is by air Risk factors Cigarettes, alcohol, renal transplant, ↑ age Clinical 2-10 day incubation, followed by an abrupt malaise, headache, myalgia, a dry, initially non-productive, later productive, cough, hemoptysis; fever to 40ºC, rigors often associated with bradycardia; less commonly, nausea, diarrhea, delirium, septicemia, abscesses, acute myocarditis, pericarditis, rhabdomyolysis DiffDx Sporadic LD mimics myoplasma pneumonia, Q fever, tularemia, plague, psittacosis, influenza and other viral pneumonias CXR Patchy, segmental, or lobar, often bilateral, alveolar infiltrates, often progressing to nodule Lab ↓ Na+, ↓ PO4–, ↑ liver enzymes, proteinuria, microscopic hematuria, relative leukocytosis, ↑ ESR, hyponatremia, ↑ ALT,
↑ AST, ↑ BR, azotemia Complications Empyema, shock, DIC, renal failure, neurologic sequelae, peripheral neuropathy Management Erythromycin, T-S, penicillin Prognosis 15-20% death w/o therapy; up to 50% death in immunocompromised Pts Poor prognostic features Tachycardia, tachypnea, WBCs
≥ 14,000/mm3, ↑ BUN, ↑ creatinine, hyponatremia, hypoxia, leukopenia, bilateral infiltrates on CXR Prevention Chlorination; UV irradiation of water supplies. See Community-acquired pneumonia, Legionella pneumophila. Cf Pontiac disease.

Legionnaire's disease

A lung disease caused by a bacterium.
Mentioned in: Erythromycins
References in periodicals archive ?
Legionnaire's disease cannot be spread from person to person and can only be contracted by breathing in contaminated water.
Miami-Dade health officials have issued an advisory for those who have recently stayed at the property to contact the department as well as their own personal physicians, especially if they have symptoms of Legionnaire's Disease.
Philip John Roberts, 59, from Cross Keys, and Linda Johnson, 52, from Barry, died from Legionnaire's disease after staying at the Culverhouse Cross hotel.
A statement issued by Health Protection Agency, Herefordshire County Council and the Herefordshire Primary Care Trust last night said: 'Sadly the second person originally diagnosed with legionnaire's disease died yesterday evening.
A death certificate, which has now been issued, confirms Legionnaire's disease contributed to her death.
Legionnaire's disease is a bacterial infection that is caught after inhaling mists from a water source that has a bacteria called Legionella in it.
A HOSPITAL has been forced to shut a cancer unit after the deadly bug which causes Legionnaire's Disease was found in the water supply.
TOPIC: At least nine patients came down with Legionnaire's disease after visiting a medical center in New Rochelle, NY, according to an article by The New York Times.
A PATIENT at the University Hospital of Wales in Cardiff is being treated for legionnaire's disease, it emerged last night.
We're confident that they have not developed legionnaire's disease since the cooling towers were shut down.
A PENSIONER died after contracting Legionnaire's disease in a holiday swimming pool.