The above table reveals that mean leak point pressure increased in significant amount postoperatively.
Mean leak point pressure is 74.2 [+ or -] 20.1cm H2O in preoperative period & 122.1 [+ or -] 18.1cm of H2O postoperatively (p=<0.0001).
Damaser, "Effects of anesthesia on cystometry and leak point pressure of the female rat," Life Sciences, vol.
On the basis of the aforementioned findings , we hypothesized the following: (1) simulated birth trauma and OVX decrease leak point pressures (LPPs) and plasma estradiol levels; (2) simulated birth trauma and OVX induce atrophy of the urogenital tract and the expression of neuronal nitric oxide synthase (nNOS) with induced nitric oxide synthase (iNOS); (3) ER[alpha] and ER[beta] expression are altered by simulated birth trauma and OVX in a mouse model of SUI.
Variables associated with the need for repeat treatment included indicators of more severe incontinence, including leak point pressure
of 60 cm [H.sub.2]O or lower (OR, 7.3), history of urethrolysis (OR, 6.2), low MUCP (OR, 3.5), VLPP of 60 cm [H.sub.2]O or lower (OR, 3.5), five or more incontinent episodes per day (OR, 3.0), and a positive empty supine test (OR, 2.7).
Low bladder compliance is clinically relevant, particularly when associated with a high detrusor leak point pressure
(discussed later in the article); this can cause upper urinary tract distress leading to ureteral reflux, hydronephrosis, upper UTIs, renal scaring, and sometimes loss of renal function.
Differences between cough and Valsalva leak point pressure
in stress incontinent women.
The procedure cured 84% of 121 patients with isolated anatomic stress urinary incontinence and 75% of 22 patients with isolated intrinsic sphincter deficiency, defined by a urethral closure pressure of less than 20 cm of water or a leak point pressure
of less than 60 cm of water.
If she leaks with that amount in the bladder with supine straining, she has a decent chance of having a low leak point pressure
. This may indicate an intrinsic sphincter deficiency "You might want to get the next level of urodynamic testing or let someone else look at those patients, because they might need a sling," he said.
Weber measures her urethral function by performing a leak point pressure
test or urethral pressure profile.
Candidates for collagen injections are identified by preprocedural testing demonstrating either a lower urethral closure pressure of less than 20 cm [H.sub.2]O or a leak point pressure
below 60 cm [H.sub.2]O.
Richter said, based on their higher Valsalva leak point pressures
and maximal urethral closure pressures (measured in the TOMUS study).