lead compound

(redirected from Lead compounds)

lead compound

A peptide, small molecule, or other agent with pharmacological or biochemical properties which suggest that it may have therapeutic potential and value as a starting point for drug development.
References in periodicals archive ?
number of lead compounds, but is not limited to a single lead compound.
Under the agreement terms, the two companies will strive to identify lead compounds against kinase targets.
Each training and compliance workshop provides these facilities a session focused on the new lead and lead compounds rule, in addition to assistance in understanding and complying with overall EPCRA section 313 regulations.
The new reporting threshold is more than 100 pounds (220 kilograms) annually for a facility emitting lead and lead compounds.
EPA issued the final rule associated with lowering the Toxics Release Inventory (TRI) reporting threshold for lead and lead compounds to 100 Ib/yr.
HPI will provide NNL with specific lead compounds and their proprietary small molecule combinatorial libraries for screening in NNL's proprietary receptor assays.
While lead-based treatments usually are not the first line of defense, he found families often administer several "fingertip"-sized doses of lead compounds daily when other empacho remedies fail.
Factors that might cause such a material difference include, among others, uncertainties related to the ability to attract and retain partners for our technologies, the identification of lead compounds, the successful preclinical development thereof, the completion of clinical trials, the FDA review process and other government regulation, our pharmaceutical collaborators' ability to successfully develop and commercialize drug candidates, competition from other pharmaceutical companies, product pricing and third-party reimbursement.
lead compounds for epilepsy and neuropathic pain, for which the Company is conducting preclinical studies;
HPI has identified several promising lead compounds through its proprietary technology," Whitehead said.
The resources of this collaboration will expedite the research and development of our lead compounds and accelerate the commercial development of Neose's complex carbohydrate manufacturing technology, both of which will help us attain our goal of becoming a fully integrated pharmaceutical company," said Dennis H.
The Company has reported the discovery of multiple tractable lead chemotypes, and now has identified lead compounds demonstrating efficacy in models of pain.