lead compound


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lead compound

A peptide, small molecule, or other agent with pharmacological or biochemical properties which suggest that it may have therapeutic potential and value as a starting point for drug development.
References in periodicals archive ?
In pharmaceuticals, lead compound obviousness analysis usually involves analyzing the substitution of a portion of a structurally similar known compound to arrive at the claimed compound.
The company's lead compound, ThGRF, is an analogue of a natural hormone known as growth hormone releasing factor.
The old reporting threshold required facilities to report lead and lead compound emissions to air, water and land if they annually manufactured or processed more than 25,000 pounds (55,000 kilograms).
If, however, a lead compound with radiolead added is stirred in water so that a tiny fraction of the molecules dissolve, that same tiny fraction of the molecules containing radio-lead also dissolves.
Carna Biosciences will handle compound screening and construct a protein expression system and CrystalGenomics will analyze the structure of Cdc7-ASK and optimize a lead compound.