Laurence-Moon-Bardet-Biedl syndrome

Laurence-Moon-Bardet-Biedl syndrome

[lôr′əns mo̅o̅n′ bärdā′ bē′dəl]
Etymology: John Z. Laurence, English ophthalmologist, 1829-1870; Robert C. Moon, American ophthalmologist, 1844-1933; Georges Bardet, French physician, b. 1885; Artur Biedl, Czechoslovakian physician, 1869-1933
a hereditary condition characterized by obesity, hypogenitalism, mental deficiency, polydactylism, and retinitis pigmentosa. It is transmitted as an autosomal-recessive trait.

Laurence-Biedl syndrome

(1) Bardet-Biedl syndrome (see there), OMIM:209900. 
(2) Laurence-Moon syndrome (see there), OMIM:245600. 

Until recently, it was common practice to consolidate these two conditions together as the Laurence-Moon-Bardet-Biedl syndrome.
References in periodicals archive ?
Electroretinography and diagnosis of the Laurence-Moon-Bardet-Biedl syndrome in childhood.
Anneba, of Erdington, Birminghan, suffered from Laurence-Moon-Bardet-Biedl syndrome.
It wasn't until four years later that his parents would discover Daniel was suffering from a rare genetic condition called Laurence-Moon-Bardet-Biedl Syndrome (LMBBS), which would leave him overweight and nearly blind.
INTRODUCTION: Laurence-Moon-Bardet-Biedl syndrome (LMBBS) is a rare, genetically heterogeneous, autosomal recessive disorder characterized by early onset retinitis pigmentosa, post axial polydactyly, central obesity, mental retardation, hypogonadism and kidney structural abnormalities or functional impairment.
CASE REPORT: Here is a joint family of 11 members, which had 7 affected members with various sub syndromes of Laurence-Moon-Bardet-Biedl Syndrome; all the affected members had supernumerary teeth which was a rare feature in this variant of Laurence-Moon-Bardet-Biedl Syndrome.
A diagnosis of Laurence-Moon-Bardet-Biedl syndrome having central obesity, postaxial polydactyly, mental retardation, retinitis pigmentosa, hypogonadism and functional renal impairment was made followed up for pubertal development for the next few years as hypogonadism is a likely problem.
Laurence-Moon-Bardet-Biedl Syndrome Network 18 Strawberry Hill Windsor, CT 06095 (203) 688-7880