lateral hypothalamic area

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lat·er·al hy·po·tha·lam·ic ar·e·a

the portion of the hypothalamus located generally lateral to a rosterocaudal line drawn through the column of the fornix and the mammillothalamic tract; contains fibers collectively comprising the medial forebrain bundle [TA] and the following nuclei: portions of the preoptic area [TA] (area preoptica [TA]), portions of the lateral tuberal nuclei [TA] (nuclei tuberales laterales [TA]), the perifornical nucleus [TA] (nucleus perifornicalis [TA]), and the tuberomammillary nucleus [TA] (nucleus tuberomammillaris [TA]).
See also: hypothalamus.
References in periodicals archive ?
Past work has linked drug addiction and other reward-seeking behaviors, such as sex and eating, to nerve cells, or neurons, that connect the lateral hypothalamus to the ventral tegmental area in the brain.
Tye and her team suspected that a neural pathway from the lateral hypothalamus to the ventral tegmental area might play an important role in compulsive overeating because these brain regions have been implicated in reward-related behaviors such as eating, sexual activity, and drug addiction.
Adenosine, acting at the A1 receptor, also acts on the perifornical lateral hypothalamus and has a regulating effect on wakefulness and somnolence, thus potentially explaining the sleepiness some patients experience after MTX dosing.
5 ml/kg, intraperitoneal) and stereotaxically implanted with a guide cannula for dialysis probe (CMA 12, Carnegie Medicine, Stockholm, Sweden) in the lateral hypothalamus (A = -1.
The MFB originates in the reticular formation (a network of nerve fibers and cells in the brainstem), extends through the VTA and through the lateral hypothalamus, and finally projects into the nucleus accumbens, the amygdala and the prefrontal cortex.
6) The posterior lateral hypothalamus contains orexin neurons that are crucial for maintaining normal wakefulness.
Alternatively, neurons of the olfactory tract extend to the amygdala, which sends fibers to the lateral hypothalamus and the NTS besides other areas (Price 2003).
Its exact mechanism is unknown, but it activates neurons in the tuberomammillary nucleus and lateral hypothalamus, resulting in histamine release, thereby promoting wakefulness (Neurosci Lett, 2003;339:143-146).
Although numerous brain areas are known to regulate feeding behavior, the lateral hypothalamus (LH) may play a key role in regulating overeating during SSS (Rolls et al, Brain Research, 1986).
Fessel and Forsyth (1963) demonstrated that electrical stimulation of the lateral hypothalamus in rats increased gamma globulin levels for up to 10 days following brain stimulation.
They bind to neuropeptides Orexin-A and Orexin-B that are produced by neurons in the lateral hypothalamus and are activated by these neuropeptides.

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