latanoprost


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latanoprost

 [lah-tan´o-prost″]
an agent applied topically to the conjunctiva in treatment of open-angle glaucoma and ocular hypertension.

latanoprost

Xalatan Ophthalmology An agent used to ↓ intraocular pressure in Pts with 1º and 2º glaucoma. See Glaucoma.

latanoprost

A PROSTAGLANDIN drug used in the form of eye drops oncee daily to control intraocular pressure in chronic simple GLAUCOMA.

prostaglandin analogues 

Drugs used in the treatment of open-angle glaucoma or ocular hypertension. At specific dosages they lower the intraocular pressure (IOP), supposedly by increasing the outflow of aqueous humour via the uveoscleral pathway. Common agents include latanoprost, travoprost, bimatoprost (a synthetic prostamide structurally related to prostaglandin) and unoprostone isopropyl. Bimatoprost reduces IOP by increasing the uveoscleral outflow as well as the trabecular outflow.
References in periodicals archive ?
"Latanoprost" is the name of a topical eye drop used to treat various forms of glaucoma and I found it printed on a cheap plastic pen in the flat of a friend I had recently moved in with, under the bed in fact.
The aim of this study is to compare the efficacy and tolerability of the four PGAs: bimatoprost (benzalkonium chloride, BAK 0.3mg/mL), latanoprost (BAK 0.2mg/mL), travoprost (polyquad), and tafluprost (BAK-free).
The inclusion criterion for the study was for patients to have used or currently using a PA eye drop (Bimatoprost 0.01%, Latanoprost 0.005%, or Travoprost 0.004%) limited to one eye (previously prescribed by an Ophthalmologist other than the PI) and had to be older than 21 years of age.
We have decided to compare the isolated effect of tafluprost on IOP, once it lias been reported that the combination of latanoprost with timolol, appeared to have little or no effect on IOP in clinically normal dogs (SMITH et al..
The third group received both the pine bark-bilberry compound and the latanoprost drops.
Aims and Objectives: The aim was to evaluate the efficacy of the fixed and unfixed combinations of latanoprost and timolol in patients of open-angle glaucoma and ocular hypertension (OH).
Timolol maleate 0.5% preparations were administered as one drop, once daily in the evening (8:00 PM) for FCs containing bimatoprost 0.03%, travoprost 0.004%, and latanoprost 0.005% and as one drop, twice daily (8:00 AM and 8:00 PM) for dorzolamide hydrochloride 2%, brinzolamide 1%, and brimonidine tartrate 0.2% combinations.
Latanoprost is a prostaglandin-F2-alpha analogue that acts as an agonist of the prostaglandin-F2-alpha receptor.
A 26-year-old asthmatic pregnant patient whose juvenile open-angle glaucoma had been controlled for 12 years with timolol, brimonidine, and latanoprost presented to the glaucoma service in her second trimester of pregnancy because of an uncontrolled IOP (44 mm Hg in both eyes) detected by her ophthalmologist.
These are Latanoprost (Approved in 1996) [Goldberg I, Cunha-Vaz J, Jakobsen JE, et al].
The glaucoma market is about to enter a phase of new growth with the arrival of first-in-class drugs, such as Aerie's Rhopressa, Bausch & Lomb's Vesneo (latanoprost bunod), and Inotek's trabodenoson into the 7MM during the forecast period, which will generate additional growth in the global glaucoma market.
Objective: To compare the intraocular pressure (IOP) lowering effect of topical drug combination (Latanoprost and Timolol) with Latanoprost alone in patients of Primary Open Angle Glaucoma (POAG).