Additionally, given the absence on physical examination of other facial, orthopedic, and cardiac findings, no syndromic explanation (e.g., Larsen Syndrome
) was considered.
Larsen Syndrome is the rare inherited disease of defect in collagen formation.
Larsen syndrome is a rare genetic disease associated with defect in collagen formation.
In this report, we present a case with Larsen syndrome, which was scheduled to undergo inguinal hernia surgery; in addition, the anesthetic management of this syndrome is discussed.
Patients with Larsen syndrome may require surgery for multiple orthopedic abnormalities (1).
Anesthesia for children with Larsen syndrome can be hazardous.
Volunteer Victoria Marshall, 32, from Lynemouth near Ashington, stayed at Crawford House from October 2012 to May 2013 while her son Dillon, 10, who suffers from Larsen syndrome
recovered from a spinal surgery operation.
Larsen syndrome is a rare congenital disorder characterized by multiple large joint dislocations and flattened facies.
Genes that have been implicated in Larsen syndrome include filamin B , whichisinvolvedinthe cytoskeletal architecture, and carbohydrate sulphotransferase 3, which has also been implicated in other skeletal dysplasias .
Larsen syndrome has been associated with a number of other anomalies, many of which have relevance to the otolaryngologist.
We present a case of Larsen syndrome being associated with ossicular malposition causing a conductive hearing loss.
She had a recent diagnosis of Larsen syndrome, and was homozygous for the CHST3 gene, for which the inheritance is autosomal recessive.