Laron-type dwarfism | definition of Laron-type dwarfism by Medical dictionary
La·ron-type dwarf·ism (lah-ron'tīp dwōrf'izm)
A disorder associated with deficiency of somatomedin C (insulinlike growth factor I) or abnormalities in receptor activity.
Laron, Zvi, Israeli pediatric endocrinologist, 1927–.
Laron-type dwarfism - dwarfism associated with absent or very low levels of somatomedin C (insulinlike growth factor I) or abnormalities in receptor activity.
References in periodicals archive
To increase the height of children with growth hormone deficiency (9) and also to treat people who suffer from IGF-1 deficiency such as Laron syndrome or Laron-type dwarfism
(short stature syndrome), recombinant IGF-1 is prescribed (8).
Characterization of the human growth hormone receptor gene and demonstration of a partial gene deletion in two patients with Laron-type dwarfism
. Proc Natl Acad Sci USA 1989; 86: 8083-8087, doi: 10.1073/pnas.86.20.8083.