Laron-type dwarfism

La·ron-type dwarf·ism

(lah-ron'tīp dwōrf'izm)

A disorder associated with deficiency of somatomedin C (insulinlike growth factor I) or abnormalities in receptor activity.

Laron,

Zvi, Israeli pediatric endocrinologist, 1927–.

Laron-type dwarfism - dwarfism associated with absent or very low levels of somatomedin C (insulinlike growth factor I) or abnormalities in receptor activity.

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References in periodicals archive ?

To increase the height of children with growth hormone deficiency (9) and also to treat people who suffer from IGF-1 deficiency such as Laron syndrome or Laron-type dwarfism (short stature syndrome), recombinant IGF-1 is prescribed (8).

Expression of recombinant human insulin-like growth factor type 1 (rhIGF-1) in Escherichia coli

Characterization of the human growth hormone receptor gene and demonstration of a partial gene deletion in two patients with Laron-type dwarfism. Proc Natl Acad Sci USA 1989; 86: 8083-8087, doi: 10.1073/pnas.86.20.8083.