Laron syndrome


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Laron syndrome

[Z. Laron, contemporary Israeli physician]
Primary insensitivity or resistance to the effects of growth hormone. It is a common cause of dwarfism. Affected individuals have high levels of circulating growth hormone, but do not make insulin-like growth factor-1 (IGF-1). They can be treated with IGF-1.
Synonym: growth hormone insensitivity syndrome
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References in periodicals archive ?
He diagnosed Brayden with Laron syndrome, a rare genetic growth disorder that causes short stature and low blood sugar.
In the 1990's, researchers at Cincinnati Children's conducted a study for a drug called "Increlex" for treatment of patients with Laron Syndrome.
Proposed possible explanations include microcephaly, Laron Syndrome or endemic hypothyroidism ("cretinism").
Jaime Guevara-Aguirre, an Ecuadorean physician, discovered the people--who have Laron syndrome and are generally less than three-and-a-half feet tall--in remote villages.
floresiensis fossils exhibit 33 skeletal symptoms of Laron syndrome, a type of insensitivity to growth hormones.
The community includes many members with Laron syndrome, a deficiency in a gene that prevents the body from using growth hormone.
Miniature humans whose prehistoric remains were recently unearthed on an Indonesian island may have had a genetic disease known as Laron syndrome.
Various genetic mutations can produce Laron syndrome, in which the body is unresponsive to growth hormone.
Un mundo pequeno / Sangre es poder - A Small World / Blood is Power (Ecuador/Mexico) This episode visits the Ecuadorian village of Balsas, where a large segment of the population suffers from Laron Syndrome, a strange genetic affliction that keeps them from growing any taller than 125 centimeters.