Langerhans cells


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Lan·ger·hans cells

(lahng'ĕr-hahnz),
1. dendritic clear cells in the epidermis, containing distinctive granules that appear rod- or racket-shaped in section, but lacking tonofilaments, melanosomes, and desmosomes; they carry surface receptors for immunoglobulin (Fc) and complement (C3), and are believed to be antigen fixing and processing cells of monocytic origin; active participants in cutaneous delayed hypersensitivity. Synonym(s): interdigitating dendritic cells
2. cells seen in eosinophilic granuloma and lymphoma of the lungs.
Synonym(s): dendritic cell

Lan·ger·hans cells

(lahng'er-hahnz selz)
1. Dendritic clear cells in the epidermis containing distinctive granules but lacking tonofilaments, melanosomes, and desmosomes; they carry surface receptors for immunoglobulin (Fc) and complement (C3), and are believed to be antigen-fixing and processing cells of monocytic origin; active participants in cutaneous delayed hypersensitivity.
2. Cells seen in eosinophilic granuloma and lymphoma of the lungs.

Langerhans cells

cells involved in the presentation of antigens to bring about an immune response; such cells are found in the skin and the gastrointestinal tract.

Langerhans,

Paul, German anatomist, 1847-1888.
islets of Langerhans - cellular masses composed of different cell types that comprise the endocrine portion of the pancreas and are the source of insulin and glucagon. Synonym(s): islet tissue; Langerhans islands; pancreatic islands; pancreatic islets
Langerhans cell granulomatosis
Langerhans cells - dendritic clear cells in the epidermis that are active participants in cutaneous delayed hypersensitivity.
Langerhans granule - a small membrane-bound granule first reported in Langerhans cells of the epidermis. Synonym(s): Birbeck granule
Langerhans islands - Synonym(s): islets of Langerhans

Langerhans cells

population of dendritic cells within epidermal stratum granulosum; function as antigen-presenting cells

Lan·ger·hans cells

(lahng'er-hahnz selz)
Dendritic clear cells in epidermis, containing distinctive granules that appear rod- or racket-shaped in section, but lacking tonofilaments, melanosomes, and desmosomes.

Langerhans cells,

n.pl the cells of the pancreas that produce insulin.
References in periodicals archive ?
But in LCH, too many Langerhans cells are produced and build up in certain parts of the body where they can form tumours or damage organs.
1) They also showed a decreased level of the kind of DNA damage that can lead to cancer, as well as a trend suggesting the preservation of Langerhans cells (key immune cells found in the epidermis, or outer layer of skin).
Histopathologically, LCH is characterized by proliferation of atypical Langerhans cells that form granulomas.
Langerhans cell sarcoma is a rare, high-grade neoplasm with overtly malignant cytological features and the Langerhans phenotype.
The Langerhans cells are arranged in loose meshworks, clusters, and individual cells, with variable numbers of eosinophils usually representing the predominant inflammatory cell in all osseous cases (Figure 10, C, D).
These combined features were diagnostic of Langerhans cell histiocytosis.
Key words: Langerhans cell histiocytosis, pneumothorax, open lung biopsy
Other adult cells included dendritic and Langerhans cells, which direct other immune cells to attack infections, and neutrophils, the most common type of white blood cell.
A recently completed double-blind, placebo-controlled study indicates that supplementation with Lyc-O-Mato tomato extract, from LycoRed, helps protect the skin against damage from UV radiation by reducing sunburn cell formation and protecting the skin's immune system by slowing down the depletion of Langerhans cells, following exposure to UVB/UVA solar simulator.
into therapeutic indications," she concluded, but admitted that for the moment it remained unclear whether Langerhans cells could be used in anti-oxygen products or cosmetics to fight free-radicals.
The protein produced by the Langerhans cells is called Langerin, and could be instrumental in curtailing transmission of the virus that is responsible for the AIDS epidemic.
The main focus is on the function of T lymphocytes, Langerhans cells and keratinocytes with other cell types briefly mentioned.

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