Langerhans cells


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Lan·ger·hans cells

(lahng'ĕr-hahnz),
1. dendritic clear cells in the epidermis, containing distinctive granules that appear rod- or racket-shaped in section, but lacking tonofilaments, melanosomes, and desmosomes; they carry surface receptors for immunoglobulin (Fc) and complement (C3), and are believed to be antigen fixing and processing cells of monocytic origin; active participants in cutaneous delayed hypersensitivity. Synonym(s): interdigitating dendritic cells
2. cells seen in eosinophilic granuloma and lymphoma of the lungs.
Synonym(s): dendritic cell

Lan·ger·hans cells

(lahng'er-hahnz selz)
1. Dendritic clear cells in the epidermis containing distinctive granules but lacking tonofilaments, melanosomes, and desmosomes; they carry surface receptors for immunoglobulin (Fc) and complement (C3), and are believed to be antigen-fixing and processing cells of monocytic origin; active participants in cutaneous delayed hypersensitivity.
2. Cells seen in eosinophilic granuloma and lymphoma of the lungs.

Langerhans cells

cells involved in the presentation of antigens to bring about an immune response; such cells are found in the skin and the gastrointestinal tract.

Langerhans,

Paul, German anatomist, 1847-1888.
islets of Langerhans - cellular masses composed of different cell types that comprise the endocrine portion of the pancreas and are the source of insulin and glucagon. Synonym(s): islet tissue; Langerhans islands; pancreatic islands; pancreatic islets
Langerhans cell granulomatosis
Langerhans cells - dendritic clear cells in the epidermis that are active participants in cutaneous delayed hypersensitivity.
Langerhans granule - a small membrane-bound granule first reported in Langerhans cells of the epidermis. Synonym(s): Birbeck granule
Langerhans islands - Synonym(s): islets of Langerhans

Langerhans cells

population of dendritic cells within epidermal stratum granulosum; function as antigen-presenting cells

Lan·ger·hans cells

(lahng'er-hahnz selz)
Dendritic clear cells in epidermis, containing distinctive granules that appear rod- or racket-shaped in section, but lacking tonofilaments, melanosomes, and desmosomes.

Langerhans cells,

n.pl the cells of the pancreas that produce insulin.
References in periodicals archive ?
Pulmonary Langerhans cell histiocytosis: emerging concepts in pathobiology, radiology, and clinical evolution of disease.
Dry eye symptoms, palpebral conjunctival inflammatory cell, and Langerhans cell relationship
Epidermis-to-dermis migration of immature Langerhans cells upon topical irritant exposure is dependent on CCL2 and CCL5.
sup][1],[2],[3] Langerhans cells are characteristically seen as large cells with clear and velvety cytoplasm, oval or kidney-shaped vesicular nuclei with irregular shapes nucleoli, frequent grooves, and indentation on Giemsa stain.
Pulmonary Langerhans cell histiocytosis: evolution of lesions on CT scans.
2009) Langerhans cells suppress contact hypersensitivity responses via cognate CD4 interaction and langerhans cell-derived IL-10.
Association of Langerhans Cell Histiocytosis with Malignant Neoplasms.
Langerhans cell histiocytosis: a clinicopathologic and immunohistochemical analysis of 258 cases.
Following a trip to her optometrist and an emergency skull biopsy, she was found to have Langerhans cell histiocytosis (LCH) - one of the rarest medical conditions in the country, which could have killed her.
Cytochemical identification of ATPase positive Langerhans cells in EDTA-separated sheets of mouse epidermis.
LCH is caused by the proliferation and accumulation of a specific histiocyte, the Langerhans cell.
The deep dermis showed no Langerhans cells (Figures 1g, 1h).

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