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An antigen-presenting dendritic cell of the epidermis, containing characteristic rod-shaped granules (Birbeck granules). Langerhans cells are thought to stimulate T cells in lymph nodes to which they migrate and also T cells in the skin.
The American Heritage® Medical Dictionary Copyright © 2007, 2004 by Houghton Mifflin Company. Published by Houghton Mifflin Company. All rights reserved.
Langerhans cellAn antigen-presenting dendritic cell found in the skin. These cells pick up and process antigen in the skin and then move to the nearest lymph node where the antigen is presented to T cells. In this way the immune system may become sensitized to a contact allergen. (Paul Wilhelm Langerhans 1847–88, German physician, who described these cells when he was a medical student.)
Collins Dictionary of Medicine © Robert M. Youngson 2004, 2005