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Guil·lain-Bar·ré syn·drome(gē-yan[h]' bă-rā'),
an acute, immune-mediated disorder of peripheral nerves, spinal roots, and cranial nerves, commonly presenting as a rapidly progressive, areflexive, relatively symmetric ascending weakness of the limb, truncal, respiratory, pharyngeal, and facial musculature, with variable sensory and autonomic dysfunction; typically reaches its nadir within 2-3 weeks, followed initially by a plateau period of similar duration, and then subsequently by gradual but complete recovery in most cases. Guillain-Barré syndrome is often preceded by a respiratory or gastrointestinal infection and is associated with albuminocytologic dissociation of the cerebral spinal fluid. Although classically considered pathologically to be an acute, inflammatory demyelinating polyradiculoneuropathy (q.v.), pure axon degeneration forms recently have been recognized.
Synonym(s): acute idiopathic polyneuritis, acute inflammatory polyneuropathy, infectious polyneuritis, Landry paralysis, Landry syndrome, Landry-Guillain-Barré syndrome, postinfectious polyneuritis
Farlex Partner Medical Dictionary © Farlex 2012
Flaccid paralysis that begins in the lower extremities and rapidly ascends to the trunk.
See also: paralysis
Medical Dictionary, © 2009 Farlex and Partners
Landry,Jean B.O., French physician, 1826-1865.
Landry-Guillain-Barré syndrome - Synonym(s): Landry syndrome
Landry paralysis - Synonym(s): Landry syndrome
Landry syndrome - marked by paresthesia of the limbs and muscular weakness or a flaccid paralysis. Synonym(s): acute idiopathic polyneuritis; Landry-Guillain-Barré syndrome; Landry paralysis
Medical Eponyms © Farlex 2012