Lacazia loboi


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Lacazia loboi

(la-koz'e-a lo'bo-i?, -lo-bo'i?, lo'bo-e?, -lo-bo'e?)
The spherical yeast that causes lobomycosis. It is structurally similar to Paracoccidioides brasiliensis. Synonym: Loboa loboi; Paracoccidioides loboii
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The clinical and phenotypic features of the uncultivated agent of lacaziosis/lobomycosis in dolphins suggested that this pathogen was the same organism as Lacazia loboi, which causes skin keloidal-like lesions in humans (1-6).
Her research interests include Lacazia loboi, Lagenidium spp.
Toward the identification, characterization and experimental culture of Lacazia loboi from Atlantic bottlenose dolphin (Tursiops truncatus).
Phylogenetic analysis of Lacazia loboi places this previously uncharacterized pathogen within the dimorphic Onygenales.
Lobomycosis is a subcutaneous mycosis caused by Lacazia loboi (L.
3,10-12) The pathogen is Lacazia loboi, a spherical homogenoeus yeast of 8-12 mm diameter, residing singly or in chains, predominantly in macrophage vacuoles.
Lacazia loboi and Rhinosporidium seeberi: a genomic perspective.
Lacazia loboi is a fungus (order Onygenales) that has not yet been cultured (1).
The taxonomic status of Lacazia loboi and Rhinosporidium seeberi has been finally resolved with the use of molecular tools.
Unfortunately, the etiologic agent of lobomycosis, Lacazia loboi (Figure), has not been cultured in vitro (10) despite exhaustive attempts, making its isolation from probable and suspected environmental sources impossible.
The causative agent is Lacazia loboi (2), a fungus of uncertain phylogeny, which causes an inflammatory infiltrate accompanied by the formation of a granuloma in which giant cells phagocytose a larger number of fungi (3,4).
The nomenclature of the fungus has been subject to ongoing debate, although a new genus, Lacazia, with Lacazia loboi as the type species, was recently proposed by Toborda et al.