The extracted data included CPG characteristics and recommendations in LUTS
This was the first study to evaluate the effects of a Se-SM combination on LUTS
in men with BPH, finding the combination to be very effective in reduction both voiding dysfunction and PSA levels after six months of treatment.
The study, called Alfone, is an ongoing, multi-center, non-comparative, observational, open-label study designed to collect, under daily practice conditions, clinical data on the safety profile and efficacy of Uroxatral in over 7,700 patients with LUTS
suggestive of BPH.
Assess the evidence for currently available medical and interventional options to treat LUTS
The most recent evidence-based recommendations in this field are the 2012 Guidelines on the Management of Male LUTS
, published by the European Association of Urology (EAU).
Overall, investigation of an international prostatitis database showed that 50% to 60% of men in the database had urinary LUTS
While antimuscarinic and/or alpha-blockade therapy is effective for symptom relief in a large proportion of patients with LUTS
associated with OAB, a substantial minority do not achieve adequate symptomatic treatment response.
It is useful for all storage LUTS
and is essential for nocturia when it is an isolated complaint.
The storage symptom component of LUTS
of overactive bladder (OAB) represents an empirical diagnosis used as the basis for initial management after assessing clinical history, physical findings, urinalysis, and other indicated evaluations.
It is important to realize that LUTS
in men may not be caused by the prostate.
Urinalysis is required to rule out diagnoses other than BPH that may cause LUTS
and may require additional diagnostic tests.
Results from the Olmsted County Study of Urinary Symptoms, a survey of men residing in the county around the Mayo Clinic, showed a prevalence of moderate to severe LUTS
(msLUTS) of 33%, 41% and 46% in men in their sixth, seventh, eighth and older decades of life.