LTBI


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LTBI

latent tuberculosis infection. Active tuberculosis may emerge in patients who have latent (inactive) infections when their immune systems fail, either because of malnutrition, or because they contract other diseases. The eradication of latent tuberculosis infection is a worldwide public health goal.
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It is reasonable to extend that to annual testing of employees to achieve the goal of early detection of LTBI.
Report LTBI to the local health department and seek advice on the appropriate tests and treatments.
It seems to offer better possibility of improved detection of LTBI, however, data on its performance in arthritis patents are limited (5-13).
Conclusion: The current study suggests that it may be possible to discriminate LTBI from active TBI by IL-2 responses to AlaDH.
The tuberculin skin test (TST) has been the standard method of diagnosing LTBI.
Initial and periodic screening for LTBI is recommended for HCWs who are coming into contact with patients, but the frequency of this is determined by the risk of the setting.
When the known cases of TB, LTBI and leprosy cases were excluded, we found none of the subjects had both infections, three had M.
They formed the following groups: TB patients (TBP), TB suspects (TBS), Mtb-exposed healthy individuals having high risk of LTBI (TB contacts, TBC), and healthy donors with no known records of Mtb exposure (HD) (Figure 1).
To address further plan of management following the positive quantiFERON TB test, a multidisciplinary approach, which included pulmonary diseases specialist, infectious diseases specialist, obstetrician, and pediatrician, was undertaken to address the following areas of concern: (1) isolation of baby from mother, (2) isolation of baby from other babies in nursery, (3) initiating LTBI (latent TB infection) treatment in baby, and (4) initiating four-drug TB regimen in the mother.
Chemoprophylactic drugs for LTBI may be either isoniazid (INH) for 9 months or rifampicin combined with INH for 3 months.
LTBI is an assumed "carrier state," in which people are infected with M.
Figure 1 illustrates the selection of patients requiring LTBI treatment.