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During the 6-year period of experience with anal cytology as part of the NGC program, there was significant improvement in the concordance rates for participants specific responses to the target diagnosis of LSIL but not HSIL (P < .
Cervical cytology exams (Pap smear tests) determined the patients' LSIL status and this was confirmed by colposcopy and biopsy.
demonstrated that while 35% of women had LSIL on Pap smear at entry, only 4% of them progressed to high-grade SIL over a 36-month follow-up period.
The correct correlation for the HSIL was higher compared to LSIL for the nurse in phase three reinforcing the Benedet et al.
Because the test can pinpoint which women are most likely to have cervical disease and need follow up, this should reduce a large number of the unnecessary, uncomfortable and costly colposcopies carried out on women with ASC-US or LSIL.
Since then, a few reports have documented its occurrence in humans, mostly in patients with negative Papanicolaou tests, occasionally with diagnoses of atypical squamous cells of undetermined significance and LSIL.
Silva Couto looked at women with cervical dysplasia, LSIL (CIN I and HPV).
The performance of p16INK4a immuno-cytochemistry (p16 Cytology) and HPV testing was analyzed on a series of 810 retrospectively collected ASC-US and LSIL cases.
6%; 862 of 2074), whereas LSIL and ASC-US results preceded 22.
Although the presence of LSIL increases the risk of cervical dysplasia, only 1% of the survey respondents said they believed that the copper T 380 and levonorgestrel intrauterine systems worsen cervical dysplasia.
Cervical cytology exams (Pap smear tests) determined the patients' LSIL status, and this was confirmed through colposcopy and biopsy.
The revised guidelines further state that for pregnant women with LSIL without suspected CIN 2-3 or cancer at the initial colposcopy, postpartum follow-up is recommended, and that additional colposcopic and cytological examinations during pregnancy are unacceptable.
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