LPAR6

LPAR6

A gene on chromosome 13q14 that encodes a G protein-coupled receptor preferentially activated by adenosine and uridine nucleotides.
References in periodicals archive ?
Based on the hypothesis of steroid dependency of the proliferation-stimulating LPAR, the researchers assessed the expressions of LPAR1 to LPAR6 in the presence of AA by propagating prostate cancer cell lines, namely PC-3 (highly metastatic) and LNCaP (low metastatic potential).
AA treatment was also verified to also target proliferative factors LPAR1, LPAR3, LPAR4, LPAR5 and LPAR6.
Mutations in the LPAR6 (MIM 609239) and LIPH (MIM 607365) genes have been reported to cause autosomal recessive WH/hypotrichosis phenotype in various families.