LPAR5 | definition of LPAR5 by Medical dictionary
LPAR5 A gene on chromosome 12p13.31 that encodes a rhodopsin-type G-protein-coupled transmembrane receptor, which transmits extracellular signals from lysophosphatidic acid into cells, mediating a wide range of intracellular activities.
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References in periodicals archive
Similarly, in rat sarcoma cells, overexpression of Lpar5
significantly reduced motility and suppressed MMP2 activation.
AA treatment was also verified to also target proliferative factors LPAR1, LPAR3, LPAR4, LPAR5
Two pairs of primers (unmethylated and methylated) for each of the lysophosphatidic acid receptor 5 (LPAR5
), paternally expressed 10 (PEG10), and solute carrier family 30 member 3 (SLC30A3) genes were designed using the MSP-specific default parameters of the MethPrimer program .
On the other hand, LPAR4, LPAR5
, and LPAR6 are expressed widely but at relatively low levels.