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A gene on chromosome 5q23.2 that encodes lamin B1, a protein highly conserved in evolution that forms part of the two-dimensional matrix of proteins located next to the inner nuclear membrane. Lamins are involved in providing nuclear stability and chromatin structure, and in gene expression.

Molecular pathology
LMNB1 mutations cause autosomal dominant adult-onset leukodystrophy (ADLD).
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.
References in periodicals archive ?
Renee Wolf, activities coordinator at Penylan House home for the elderly in Cardiff, where Hannah will be playing said: "We always look forward to the performances provided by LMN as the standard is so high and the musicians are all so warm and friendly."
The alterations of F wave characteristics need to be verified in further studies with patients with pure LMN lesions as control groups, such as patients with Hirayama disease, Kennedy disease or spinal muscular atrophy, though such patients with matched age and disease duration are difficult to find.
LMN Dance Group, one of the country's premier dance groups, taught the audience the 'Oreo' dance during the event.
Citing the indictment papers, the department said the defendants and their conspirators used various jewelry businesses--including Last Chance Jewelers and LMN Jewelers--to design and manufacture jewelry in the Native-American style at factories in the Philippines where Filipinos made all of the jewelry.
The renovations were designed by Seattle-based LMN Architects.
The other LMN performances are MK Duo, who are Roberto Kuhn and Callum Morton-Teng on Wednesday, March 13, and Voice and Verse, who are Laura McFall and Kristine Donnan on Wednesday, June 12.
Gillian Green, auditions director for Live Music Now (LMN), was introduced to Bohana during her student days at Cardiff University.
The top managers at both XYZ and LMN designed their scorecards for the organization as a whole and helped the branch or department devise complementary scorecards.
LMN, a veteran of 50 other convention center designs all over the world, contributed its substantial experience working with the specific building type.
and 1 a.m., LMN) A young painter is tortured by a violent entity; a teenage girl is threatened by two mysterious children during a thunderstorm.
with Amyotrophic lateral sclerosis both UMN Yes(3) and LMN type Other family members: All have normal teeth pattern and number.