BIRC7

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BIRC7

A gene on chromosome 20q13.3 that encodes a member of the apoptosis inhibitor protein (IAP) family, which contains a single copy of a baculovirus IAP repeat (BIR), which is essential for its inhibitory activity and caspase interactions, as well as a RING-type zinc finger domain, which may enhance its anti-apoptotic activity. BIRC7 protects cells against apoptosis induced by TNF, adriamycin, etoposide, staurosporine and other chemicals by activating MAPK8/JNK1, and possibly also MAPK9/JNK2.
References in periodicals archive ?
The bumper does not exactly look a hot contest and, with Ruby Walsh on board, it should pay to side with the Willie Mullins-trained LIVIN JOY.
LIVIN THE DREAM: The; Lions roar after O'Brien's goal