lissencephaly type 3

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lissencephaly type 3

A hereditary brain disorder (OMIM:611603) characterised by a smooth brain surface due to the absence (agyria) or reduction (pachygyria) of the cerebral gyri (surface convolutions); laminar heterotopia, usually associated with psychomotor retardation; severe mental retardation; variable presence of seizures; and defects of the corpus callosum, hippocampus, cerebellar vermis and brainstem.
References in periodicals archive ?
01); the LIS1 and LIS3 groups, even presenting lower values than CON group, were not statistically different.
01) of fatty acid profile in experimental LIS1, LIS2 and LIS3 groups, showing a decrease of saturated fatty acids (SFA) and an increase of polyunsaturated fatty acids (PUFAs); even the n-3 and n-6 fatty acids increased (Pless than 0.
2005), it can assume that the lack of effect on TBARS meat values in LIS3 group, could be due to the reaching of threshold dose (30 g/kg feed); while non-antioxidant activity in LIS1 group, may be due to the minimum supplement dose used (10 g/kg feed).