LIPA

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LIPA

A gene on chromosome 10q23.2 that encodes lipase A, the lysosomal acid lipase (i.e., cholesterol ester hydrolase) that catalyses the hydrolysis of cholesteryl esters and triglycerides in lysosomes.

Molecular pathology
LIPA mutations are linked to CESD and Wolman disease.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.
References in periodicals archive ?
For the purpose, isolates giving discordant results between phenotypic susceptibility and LiPA were revived on 7H10 agar for re-testing by phenotypic method and nucleic acid sequencing.
While phenotypic proportion method identified 49.1% and 54.6% of the 108 strains as resistant to RIF and INH respectively (Table-1), using the LiPA, the corresponding resistance rates were 47.2% and 41.7%.
Table-1: Comparison of LiPA and phenotypic susceptibility for INH and RIF resistance.
Paul would not have progressed with Lipa without this support."
Says Mark: "We always believed Lipa would be a success, but we didn't realise just how much the students would believe in it.
"Lipa alumni include Haley Doyle, who is currently a lead in Mamma Mia in the West End' Lindsay Inglesby, a dance graduate who decided to go into choreography and started her own school as well as teaching at Lipa and Geordie Michael Imerson who is to star in Billy Liar at the Playhouse next month."