CDH17

(redirected from LI-cadherin)

CDH17

A gene on chromosome 8q22.1 that encodes cadherin 17, which is a component of the GI tract and pancreatic ducts, acting as an intestinal proton-dependent peptide transporter in the first step in oral absorption of medically important peptide-based drugs. Cadherin 17 may also play a role in the morphological organisation of the liver and intestine.
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All CDH genes (n = 27) screened in this study include CDH1 (E-cadherin), CDH2 (N-cadherin), CDH3 (P-cadherin), CDH4 (R-cadherin), CDH5 (VE-cadherin), CDH6 (K-cadherin), CDH7 (cadherin 7), CDH8 (cadherin 8), CDH9 (T1-cadherin), CDH10 (T2-cadherin), CDH11 (OB-cadherin), CDH12 (N-cadherin 2), CDH13 (H-cadherin), CDH15 (M-cadherin), CDH16 (KSP-cadherin), CDH17 (LI-cadherin), CDH18 (cadherin 18), CDH20 (cadherin 20), PCDHGA12 (CDH21), CDH22 CDH23 CDH24 DCHS1 (CDH19, or CDH25), CDH26 DCHS2 (CDH27), CDHR3 (CDH28), and CDHR4 (CDH29).
Baumgartner, "Possible roles of LI-Cadherin in the formation and maintenance of the intestinal epithelial barrier," Tissue Barriers, vol.
A study on the expression of LI-cadherin in precancerous lesion and gastric cancer.
[Expression of E-cadherin and LI-cadherin in human gastric carcinoma and prognostic significance].
Cadherin-17 (CDH17), also known as Li-cadherin (liverintestine cadherin), is a member of the cadherin superfamily and is a calcium-dependent transmembrane glycoprotein.
LI-cadherin gene expression during mouse intestinal development.