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Limb-girdle muscular dystrophy (LGMD)

This form of muscular dystrophy begins in late childhood to early adulthood and affects both men and women, causing weakness in the muscles around the hips and shoulders.
Mentioned in: Muscular Dystrophy
References in periodicals archive ?
At this time, no special dietary restrictions or additions are known to help in LGMD.
Unfortunately, eating more protein has no effect on any of the proteins missing in LGMD.
A doctor may advise a weight reduction or weight stabilization diet for some people with LGMD.
A physical therapy program is usually part of the treatment for LGMD.
In LGMD, certain kinds of stress-causing exercises may actually hasten muscle damage.
On being told they have a genetic disorder such as LGMD, bewildered patients often ask, "But it doesn't run in the family, so how could it be genetic?
LGMD can nm in a family, even if only one person in the biological family has it.
LGMD can be inherited in one of two basic ways, known as the autosomal dominant pattern and the autosomal recessive pattern.
A recessive form of LGMD can show up in one person when there's no family history.
Just to make things a little more complicated, a person with LGMD may have a brand new genetic mutation (after all, they have to start somewhere), so there may really be no family history or even carriers of the disorder in the family.
The details of inheritance risks for any particular form of LGMD depend on many circumstances, including exactly which type of LGMD has been diagnosed.
When any of the proteins shown here in yellow-orange are missing or nonfunctional, LGMD is the result.